PMID- 17362971
OWN - NLM
STAT- MEDLINE
DCOM- 20070531
LR  - 20090115
IS  - 0021-9673 (Print)
IS  - 0021-9673 (Linking)
VI  - 1147
IP  - 2
DP  - 2007 Apr 20
TI  - Analysis of carbamate and phenylurea pesticide residues in fruit juices by 
      solid-phase microextraction and liquid chromatography-mass spectrometry.
PG  - 135-43
AB  - A new analysis method to detect carbamates and phenylurea pesticide residues in 
      fruit juices was developed using solid-phase microextraction (SPME) coupled with 
      liquid chromatography-single quadrupole mass spectrometry (LC/MS) and liquid 
      chromatography-quadrupole ion trap mass spectrometry (LC/QIT-MS). The pesticide 
      residues present in watery matrices as fruit juices were extracted using three 
      types of fibers: 50-microm Carbowax/templated resin (CW/TPR), 60-mum 
      poly(dimethylsiloxane)/divinylbenzene (PDMS/DVB) and 85-microm polyacrylate. The 
      different extraction conditions were evaluated choosing as the best parameters 90 
      min (time), 20 degrees C (temperature) and 1 ml (volume). After extraction, the 
      desorption (in a static mode) was performed in the specific interface chamber 
      SPME/HPLC, previously filled with 70% methanol and 30% water. The best 
      recoveries, evaluated at two fortification levels (0.2 and 0.5 mg kg(-1)) in 
      fruit juices, were obtained using PDMS/DVB and CW/TPR fibers, and ranged from 25 
      to 82% (monolinuron, diuron and diethofencarb), with relative standard deviations 
      (RSDs) from 1 to 17%. All the limits of quantification (LOQs) were in the range 
      of 0.005-0.05 microg ml(-1) and, in any case, equal to, or lower than, maximum 
      residue limits (MRLs) established by Italian and Spanish legislations. The mass 
      spectrometry analyses were carried out using an electrospray ionization (ESI) 
      source operating in the positive mode both for single quadrupole and for QIT mass 
      analysers, operating in selected ion monitoring (SIM) and in multiple reaction 
      monitoring (MRM) modes, respectively. The proposed new method can be applied to 
      the determination of selected pesticides in real samples of fruit juices.
FAU - Sagratini, Gianni
AU  - Sagratini G
AD  - Dipartimento di Scienze Chimiche, Facolta di Farmacia, Universita di Camerino, 
      via S.Agostino 1, 62032 Camerino, Italy. gianni.sagratini@unicam.it 
      <gianni.sagratini@unicam.it>
FAU - Manes, Jordi
AU  - Manes J
FAU - Giardina, Dario
AU  - Giardina D
FAU - Damiani, Pietro
AU  - Damiani P
FAU - Pico, Yolanda
AU  - Pico Y
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20070224
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Carbamates)
RN  - 0 (Pesticide Residues)
RN  - 0 (Phenylurea Compounds)
SB  - IM
MH  - Beverages/*analysis
MH  - Carbamates/*analysis
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Mass Spectrometry/*methods
MH  - Pesticide Residues/*analysis
MH  - Phenylurea Compounds/*analysis
EDAT- 2007/03/17 09:00
MHDA- 2007/06/01 09:00
CRDT- 2007/03/17 09:00
PHST- 2006/12/22 00:00 [received]
PHST- 2007/02/14 00:00 [revised]
PHST- 2007/02/19 00:00 [accepted]
PHST- 2007/03/17 09:00 [pubmed]
PHST- 2007/06/01 09:00 [medline]
PHST- 2007/03/17 09:00 [entrez]
AID - S0021-9673(07)00363-9 [pii]
AID - 10.1016/j.chroma.2007.02.066 [doi]
PST - ppublish
SO  - J Chromatogr A. 2007 Apr 20;1147(2):135-43. doi: 10.1016/j.chroma.2007.02.066. 
      Epub 2007 Feb 24.