PMID- 17366823
OWN - NLM
STAT- MEDLINE
DCOM- 20070502
LR  - 20240419
IS  - 0091-6765 (Print)
IS  - 1552-9924 (Electronic)
IS  - 0091-6765 (Linking)
VI  - 115
IP  - 1
DP  - 2007 Jan
TI  - Increased rate of hospitalization for diabetes and residential proximity of 
      hazardous waste sites.
PG  - 75-9
AB  - BACKGROUND: Epidemiologic studies suggest that there may be an association 
      between environmental exposure to persistent organic pollutants (POPs) and 
      diabetes. OBJECTIVE: The aim of this study was to test the hypothesis that 
      residential proximity to POP-contaminated waste sites result in increased rates 
      of hospitalization for diabetes. METHODS: We determined the number of 
      hospitalized patients 25-74 years of age diagnosed with diabetes in New York 
      State exclusive of New York City for the years 1993-2000. Descriptive statistics 
      and negative binomial regression were used to compare diabetes hospitalization 
      rates in individuals who resided in ZIP codes containing or abutting hazardous 
      waste sites containing POPs ("POP" sites); ZIP codes containing hazardous waste 
      sites but with wastes other than POPs ("other" sites); and ZIP codes without any 
      identified hazardous waste sites ("clean" sites). RESULTS: Compared with the 
      hospitalization rates for diabetes in clean sites, the rate ratios for diabetes 
      discharges for people residing in POP sites and "other" sites, after adjustment 
      for potential confounders were 1.23 [95% confidence interval (CI), 1.15-1.32] and 
      1.25 (95% CI, 1.16-1.34), respectively. In a subset of POP sites along the Hudson 
      River, where there is higher income, less smoking, better diet, and more 
      exercise, the rate ratio was 1.36 (95% CI, 1.26-1.47) compared to clean sites. 
      CONCLUSIONS: After controlling for major confounders, we found a statistically 
      significant increase in the rate of hospitalization for diabetes among the 
      population residing in the ZIP codes containing toxic waste sites.
FAU - Kouznetsova, Maria
AU  - Kouznetsova M
AD  - Department of Epidemiology and Biostatistics, School of Public Health, University 
      at Albany, Rensselaer, New York 12144-3429, USA.
FAU - Huang, Xiaoyu
AU  - Huang X
FAU - Ma, Jing
AU  - Ma J
FAU - Lessner, Lawrence
AU  - Lessner L
FAU - Carpenter, David O
AU  - Carpenter DO
LA  - eng
GR  - D43 TW000636/TW/FIC NIH HHS/United States
GR  - TW00636/TW/FIC NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PL  - United States
TA  - Environ Health Perspect
JT  - Environmental health perspectives
JID - 0330411
RN  - 0 (Hazardous Waste)
SB  - IM
CIN - Environ Health Perspect. 2008 Jan;116(1):A18; author reply A18-9. PMID: 18197278
MH  - Adult
MH  - Black or African American
MH  - Aged
MH  - Diabetes Mellitus/*epidemiology
MH  - Environmental Exposure
MH  - Female
MH  - *Hazardous Waste
MH  - Hospitalization/*trends
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - New York
MH  - Residence Characteristics
MH  - Rivers
MH  - White People
PMC - PMC1797837
EDAT- 2007/03/21 09:00
MHDA- 2007/05/03 09:00
PMCR- 2007/01/01
CRDT- 2007/03/21 09:00
PHST- 2007/03/21 09:00 [pubmed]
PHST- 2007/05/03 09:00 [medline]
PHST- 2007/03/21 09:00 [entrez]
PHST- 2007/01/01 00:00 [pmc-release]
AID - ehp0115-000075 [pii]
AID - 10.1289/ehp.9223 [doi]
PST - ppublish
SO  - Environ Health Perspect. 2007 Jan;115(1):75-9. doi: 10.1289/ehp.9223.