PMID- 17366870
OWN - NLM
STAT- MEDLINE
DCOM- 20070417
LR  - 20161124
IS  - 1110-0583 (Print)
IS  - 1110-0583 (Linking)
VI  - 36
IP  - 2 Suppl
DP  - 2006 Aug
TI  - Allergic reactions in patients suffering from asthma induced by house dust mites 
      which treatment by juvenile hormone.
PG  - 31-48
AB  - The effect of Juvenile hormone analogue, Admiral "pyriproxyfen", which acts as a 
      protein de-naturing agent, on the protein patterns of D. farinae was studied on 
      allergic reactions in patients with HDM asthma, and in mice injected twice 
      (within 10 days) with mite crude extracts. Total protein concentrations and 
      protein patterns were different in normal and admiral-treated mites. This may 
      result in reducing the allergenic of treated mites. Histamine release, total 
      immunoglobulin E (IgE), specific immunoglobulin E (S-IgE), eosinophil cationic 
      protein (ECP), and absolute eosinophil count (AEC) were determined for moderate 
      and severe HDM asthma-tics compared to check cases. These parameters had higher 
      levels in asthmatic patients than in normal (check) individuals. Injection of 
      mice with normal adult extracts of D. farinae resulted in significantly higher 
      levels of histamine, S-IgE and ECP than in the check animals. Skin reactions were 
      observed in all of the mice injected with normal or treated D. farinae extracts.
FAU - Mazyad, Said A M
AU  - Mazyad SA
AD  - Research and Training Center on Vectors of Diseases, Ain Shams University, Cairo 
      11566, Egypt.
FAU - Mohammad, Khairy A
AU  - Mohammad KA
FAU - Khalil, Hazem H M
AU  - Khalil HH
LA  - eng
PT  - Journal Article
PL  - Egypt
TA  - J Egypt Soc Parasitol
JT  - Journal of the Egyptian Society of Parasitology
JID - 8102141
RN  - 0 (Pyridines)
RN  - 37341-29-0 (Immunoglobulin E)
RN  - 3Q9VOR705O (pyriproxyfen)
RN  - EC 3.1.27.- (Eosinophil Cationic Protein)
SB  - IM
MH  - Adolescent
MH  - Animals
MH  - Asthma/*drug therapy
MH  - Child
MH  - Child, Preschool
MH  - Eosinophil Cationic Protein/immunology
MH  - Eosinophils/immunology
MH  - Female
MH  - Histamine Release/immunology
MH  - Humans
MH  - Immunoglobulin E/immunology
MH  - Infant
MH  - Male
MH  - Mice
MH  - Pyridines/*therapeutic use
MH  - Pyroglyphidae/*immunology
EDAT- 2007/03/21 09:00
MHDA- 2007/04/18 09:00
CRDT- 2007/03/21 09:00
PHST- 2007/03/21 09:00 [pubmed]
PHST- 2007/04/18 09:00 [medline]
PHST- 2007/03/21 09:00 [entrez]
PST - ppublish
SO  - J Egypt Soc Parasitol. 2006 Aug;36(2 Suppl):31-48.