PMID- 17369000
OWN - NLM
STAT- MEDLINE
DCOM- 20070801
LR  - 20240420
IS  - 1570-0232 (Print)
IS  - 1873-376X (Electronic)
IS  - 1570-0232 (Linking)
VI  - 852
IP  - 1-2
DP  - 2007 Jun 1
TI  - Development and validation of a disk solid phase extraction and gas 
      chromatography-mass spectrometry method for MDMA, MDA, HMMA, HMA, MDEA, 
      methamphetamine and amphetamine in sweat.
PG  - 450-8
AB  - We describe the development and validation of a method for the simultaneous 
      quantification of 3,4-methylenedioxymethamphetamine (MDMA), 
      3,4-methylenedioxyamphetamine (MDA), 3-hydroxy-4-methoxymethamphetamine (HMMA), 
      3-hydroxy-4-methoxyamphetamine (HMA), 3,4-methylenedioxyethylamphetamine (MDEA), 
      methamphetamine (MAMP) and amphetamine (AMP) in sweat. Drugs were eluted from 
      PharmChek sweat patches with sodium acetate buffer, extracted with disk solid 
      phase extraction and analyzed using GC/MS-EI with selected ion monitoring. Limits 
      of quantification (LOQ) for MDMA, MDEA, MAMP and AMP were 2.5 ng/patch, and 5 
      ng/patch for MDA, HMA and HMMA. This fully validated procedure was more sensitive 
      than previously published analytical methods and permitted the simultaneous 
      analysis of multiple amphetamine analogs in human sweat.
FAU - De Martinis, Bruno S
AU  - De Martinis BS
AD  - Department of Pathology, Faculty of Medicine of Ribeirao Preto, University of Sao 
      Paulo, Center of Legal Medicine, Ribeirao Preto, SP 14051-140, Brazil.
FAU - Barnes, Allan J
AU  - Barnes AJ
FAU - Scheidweiler, Karl B
AU  - Scheidweiler KB
FAU - Huestis, Marilyn A
AU  - Huestis MA
LA  - eng
GR  - Z01 DA000412-10/Intramural NIH HHS/United States
GR  - Z01 DA000468-04/Intramural NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Intramural
PT  - Research Support, Non-U.S. Gov't
PT  - Validation Study
DEP - 20070215
PL  - Netherlands
TA  - J Chromatogr B Analyt Technol Biomed Life Sci
JT  - Journal of chromatography. B, Analytical technologies in the biomedical and life 
      sciences
JID - 101139554
RN  - 0 (Amphetamines)
SB  - IM
MH  - Amphetamines/*analysis
MH  - Gas Chromatography-Mass Spectrometry
MH  - Humans
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Sweat/*chemistry
PMC - PMC2883875
MID - NIHMS25565
EDAT- 2007/03/21 09:00
MHDA- 2007/08/02 09:00
PMCR- 2010/06/11
CRDT- 2007/03/21 09:00
PHST- 2006/11/15 00:00 [received]
PHST- 2007/01/19 00:00 [revised]
PHST- 2007/02/04 00:00 [accepted]
PHST- 2007/03/21 09:00 [pubmed]
PHST- 2007/08/02 09:00 [medline]
PHST- 2007/03/21 09:00 [entrez]
PHST- 2010/06/11 00:00 [pmc-release]
AID - S1570-0232(07)00118-3 [pii]
AID - 10.1016/j.jchromb.2007.02.017 [doi]
PST - ppublish
SO  - J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jun 1;852(1-2):450-8. doi: 
      10.1016/j.jchromb.2007.02.017. Epub 2007 Feb 15.