PMID- 17375874
OWN - NLM
STAT- MEDLINE
DCOM- 20070425
LR  - 20161020
IS  - 0884-6812 (Linking)
VI  - 29
IP  - 1
DP  - 2007 Feb
TI  - Consequences of epididymal ligation on prepubertal rats.
PG  - 50-6
AB  - OBJECTIVE: To study prospectively experimental effects of unilateral epididymal 
      obstruction on testis and epididymis histopathologically in prepubertal rats. 
      STUDY DESIGN: Organ weights, mean seminiferous tubule diameter (MSTD), mean 
      ductus epididymis diameter (MDED), mean tubular biopsy scores (MTBS) and 
      histopathology of 21 male albino Wistar rats were compared with the 
      immunostaining affinity of anti-desmin, anti-vimentin, anti-laminin and 
      anti-collagen antibodies. RESULTS: Statistical analysis of mean weight of testes, 
      MTBS, mean epididymal weight, MDED and MSTD was significant. Evaluation of testis 
      and epididymis revealed cellular damage, basal membrane impairment and 
      granulomatous infiltration. CONCLUSION: Histopathologic alterations with MSTD are 
      early indicators for ipsilateral and contralateral injury. Even the presence of 
      criteria such as intactness and cellular integrity does not guarantee there is no 
      sperm leakage or immunologic damage. Therefore the impairment of basal integrity 
      is a switch code in determining spermatogenic failure.
FAU - Aktug, Huseyin
AU  - Aktug H
AD  - Department of Histology and Embryology, Ege University Faculty of Medicine, 
      Izmir, Turkey. haktug35@yahoo.com.tr
FAU - Ozdedeli, Kaan
AU  - Ozdedeli K
FAU - Altay, Baris
AU  - Altay B
FAU - Cureklibatur, Ibrahim
AU  - Cureklibatur I
FAU - Turna, Burak
AU  - Turna B
FAU - Yilmaz, Ozlem
AU  - Yilmaz O
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Anal Quant Cytol Histol
JT  - Analytical and quantitative cytology and histology
JID - 8506819
SB  - IM
MH  - Animals
MH  - Constriction, Pathologic/pathology
MH  - Disease Models, Animal
MH  - Epididymis/*pathology
MH  - Genital Diseases, Male/*pathology
MH  - Immunohistochemistry
MH  - Ligation
MH  - Male
MH  - Rats
MH  - Rats, Wistar
MH  - Testis/*pathology
EDAT- 2007/03/23 09:00
MHDA- 2007/04/26 09:00
CRDT- 2007/03/23 09:00
PHST- 2007/03/23 09:00 [pubmed]
PHST- 2007/04/26 09:00 [medline]
PHST- 2007/03/23 09:00 [entrez]
PST - ppublish
SO  - Anal Quant Cytol Histol. 2007 Feb;29(1):50-6.