PMID- 17383343
OWN - NLM
STAT- MEDLINE
DCOM- 20070412
LR  - 20071115
IS  - 1552-6259 (Electronic)
IS  - 0003-4975 (Linking)
VI  - 83
IP  - 4
DP  - 2007 Apr
TI  - Improved health-related quality of life and functional status after surgical 
      ventricular restoration.
PG  - 1381-7
AB  - BACKGROUND: Surgical ventricular restoration (SVR) has been shown to improve 
      hemodynamics and survival among patients with coronary artery disease, left 
      ventricular aneurysm, and heart failure. The aim of this study was to investigate 
      functional status and health-related quality of life after SVR. METHODS: Over a 
      period of 2 years beginning in March 2003, 23 patients with left ventricular 
      aneurysm and depressed left ventricular function were included in a prospective 
      study. Functional status and quality of life was analyzed preoperatively, 6 
      months postoperatively, and at late follow-up by assessment of New York Heart 
      Association (NYHA) functional class, 6-minute walk test, and the Medical Outcome 
      Study 36-Item Short Form. RESULTS: There was no early mortality. Before surgery, 
      17 patients (74%) were in NYHA class III to IV; and 6 months after SVR, 20 
      patients (87%) were in NYHA class I to II (p < 0.001). At late follow-up, (mean, 
      22 months postoperatively), all patients alive (n = 20) were in NYHA class I to 
      II. Mean 6-minute walk distance increased by 41 meters (p = 0.06) at 6 months 
      postoperatively and by 57 meters (p = 0.03) at late follow-up. Quality of life, 
      assessed by the physical component summary score of the Medical Outcome Study 
      36-Item Short Form, improved significantly (p = 0.04) at 6 months 
      postoperatively. A significant and clinically relevant improvement in both 
      physical aspects (+25%, p < 0.001) and mental aspects (+37%, p = 0.003) of 
      quality of life was found at late follow-up. CONCLUSIONS: Functional status and 
      quality of life improved 6 months after SVR, and the improvement was sustained at 
      late follow-up almost 2 years after surgery.
FAU - Sartipy, Ulrik
AU  - Sartipy U
AD  - Department of Cardiothoracic Surgery and Anesthesiology, Karolinska University 
      Hospital, Stockholm, Sweden. ulrik.sartipy@karolinska.se
FAU - Albage, Anders
AU  - Albage A
FAU - Lindblom, Dan
AU  - Lindblom D
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Netherlands
TA  - Ann Thorac Surg
JT  - The Annals of thoracic surgery
JID - 15030100R
SB  - IM
CIN - Ann Thorac Surg. 2007 Apr;83(4):1387-8. PMID: 17383344
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Aged, 80 and over
MH  - Coronary Angiography
MH  - Echocardiography, Doppler
MH  - Female
MH  - Heart Failure/diagnosis/mortality/*surgery
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Myocardial Revascularization/*methods/mortality
MH  - Probability
MH  - Prognosis
MH  - Prospective Studies
MH  - *Quality of Life
MH  - Risk Assessment
MH  - Severity of Illness Index
MH  - Sex Factors
MH  - Statistics, Nonparametric
MH  - Stroke Volume
MH  - Survival Rate
MH  - Sweden
MH  - Time Factors
MH  - Treatment Outcome
MH  - Ventricular Dysfunction, Left/diagnosis/mortality/*surgery
MH  - Ventricular Remodeling/*physiology
EDAT- 2007/03/27 09:00
MHDA- 2007/04/14 09:00
CRDT- 2007/03/27 09:00
PHST- 2006/09/18 00:00 [received]
PHST- 2006/11/09 00:00 [revised]
PHST- 2006/11/13 00:00 [accepted]
PHST- 2007/03/27 09:00 [pubmed]
PHST- 2007/04/14 09:00 [medline]
PHST- 2007/03/27 09:00 [entrez]
AID - S0003-4975(06)02284-3 [pii]
AID - 10.1016/j.athoracsur.2006.11.039 [doi]
PST - ppublish
SO  - Ann Thorac Surg. 2007 Apr;83(4):1381-7. doi: 10.1016/j.athoracsur.2006.11.039.