PMID- 17383544 OWN - NLM STAT- MEDLINE DCOM- 20070606 LR - 20070326 IS - 0065-2776 (Print) IS - 0065-2776 (Linking) VI - 93 DP - 2007 TI - Lung dendritic cell migration. PG - 265-78 AB - Dendritic cells (DCs) are crucial in regulating the immune response by bridging innate and adaptive immunity. DCs are constantly migrating from the blood to the lungs and from the lungs to the draining lymph nodes. How DCs populate the lung in the absence of inflammation and how they are recruited there during inflammation remain unclear. Since DCs play a central role in immune responses, both under steady-state and inflammatory conditions, detailed characterization of their migratory behavior may be essential for the development of future therapeutic strategies. FAU - Hammad, Hamida AU - Hammad H AD - Department of Pulmonary Medicine, Erasmus Medical Center, Dr Molewaterplein, 50, 3015 GE Rotterdam, The Netherlands. FAU - Lambrecht, Bart N AU - Lambrecht BN LA - eng PT - Journal Article PT - Review PL - United States TA - Adv Immunol JT - Advances in immunology JID - 0370425 SB - IM MH - Animals MH - Cell Movement/*immunology MH - Dendritic Cells/*immunology MH - Humans MH - Inflammation/immunology MH - Lung/*cytology/*immunology MH - Lymph Nodes/immunology RF - 90 EDAT- 2007/03/27 09:00 MHDA- 2007/06/07 09:00 CRDT- 2007/03/27 09:00 PHST- 2007/03/27 09:00 [pubmed] PHST- 2007/06/07 09:00 [medline] PHST- 2007/03/27 09:00 [entrez] AID - S0065-2776(06)93007-7 [pii] AID - 10.1016/S0065-2776(06)93007-7 [doi] PST - ppublish SO - Adv Immunol. 2007;93:265-78. doi: 10.1016/S0065-2776(06)93007-7.