PMID- 17383907 OWN - NLM STAT- MEDLINE DCOM- 20071214 LR - 20220318 IS - 1063-4584 (Print) IS - 1063-4584 (Linking) VI - 15 IP - 8 DP - 2007 Aug TI - Responsiveness and minimally important change for the Manchester-Oxford foot questionnaire (MOXFQ) compared with AOFAS and SF-36 assessments following surgery for hallux valgus. PG - 918-31 AB - OBJECTIVES: To assess responsiveness and minimally important change (MIC) for the Manchester-Oxford foot questionnaire (MOXFQ) using anchor and distribution-based approaches. Responsiveness and estimates of minimal clinically important difference (MCID) and minimal detectable change are compared with those from the Short-Form 36 (SF-36) and American Orthopaedic Foot & Ankle Society (AOFAS) measures. METHODS: A prospective observational study of 91 consecutive patients (125 foot operations) undergoing hallux valgus surgery at an orthopaedic hospital. Pre- and 12 month post-surgery, patients completed the MOXFQ and SF-36, and foot surgeons assessed all four AOFAS scores corresponding to four regions of the foot. Transition items were asked about perceived changes compared with before surgery. RESULTS: Mean changes in all domains of each instrument were statistically significant, but foot-specific MOXFQ and AOFAS domains produced much larger effect sizes (>1) than any SF-36 domains, indicating superior responsiveness. Clear associations occurred between transition items and all MOXFQ and AOFAS scores, but with only one (physical function) SF-36 domain. Anchor and distribution-based approaches identified generally comparable measures of MIC, which for the MOXFQ and AOFAS domains were between 1 and 2 standard error of measurement. In metric terms, the MCIDs were 16, 12, and 24 for the MOXFQ Walking/standing, Pain, and Social Interaction domains, respectively. CONCLUSIONS: For hallux valgus surgery, the MOXFQ is highly responsive. Performance is comparable to the AOFAS and notably better than the generic SF-36. Study estimates of MIC for the MOXFQ are useful to inform sample-size calculations for future clinical trials. FAU - Dawson, J AU - Dawson J AD - Department of Public Health, University of Oxford, Old Road Campus, Headington, Oxford, UK. jill.dawson@dphpc.ox.ac.uk FAU - Doll, H AU - Doll H FAU - Coffey, J AU - Coffey J FAU - Jenkinson, C AU - Jenkinson C CN - Oxford and Birmingham Foot and Ankle Clinical Research Group LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Validation Study DEP - 20070326 PL - England TA - Osteoarthritis Cartilage JT - Osteoarthritis and cartilage JID - 9305697 SB - IM EIN - Osteoarthritis Cartilage. 2011 Jul 19(7):920 MH - Activities of Daily Living MH - Adult MH - Aged MH - Hallux Valgus/*psychology/*surgery MH - Humans MH - Middle Aged MH - Motor Activity MH - Pain, Postoperative/psychology MH - Prospective Studies MH - *Quality of Life MH - ROC Curve MH - Reproducibility of Results MH - Surveys and Questionnaires/*standards EDAT- 2007/03/27 09:00 MHDA- 2007/12/15 09:00 CRDT- 2007/03/27 09:00 PHST- 2006/10/09 00:00 [received] PHST- 2007/02/04 00:00 [accepted] PHST- 2007/03/27 09:00 [pubmed] PHST- 2007/12/15 09:00 [medline] PHST- 2007/03/27 09:00 [entrez] AID - S1063-4584(07)00062-3 [pii] AID - 10.1016/j.joca.2007.02.003 [doi] PST - ppublish SO - Osteoarthritis Cartilage. 2007 Aug;15(8):918-31. doi: 10.1016/j.joca.2007.02.003. Epub 2007 Mar 26.