PMID- 17386931
OWN - NLM
STAT- MEDLINE
DCOM- 20070621
LR  - 20090115
IS  - 0021-9673 (Print)
IS  - 0021-9673 (Linking)
VI  - 1149
IP  - 2
DP  - 2007 May 18
TI  - Optimisation of a microwave-assisted extraction method for the simultaneous 
      determination of haloanisoles and halophenols in cork stoppers.
PG  - 138-44
AB  - This study presents a method based on the use of microwave-assisted extraction 
      (MAE) for the quantitative analysis of 2,4,6-trichloroanisole (TCA), 
      2,3,4,6-tetrachloroanisole (TeCA), pentachloroanisole (PCA), 
      2,4,6-tribromoanisole (TBA), 2,4,6-trichlorophenol (TCP), 
      2,3,4,6-tetrachlorophenol (TeCP), pentachlorophenol (PCP) and 
      2,4,6-tribromophenol (TBP) in cork stoppers. The influential parameters of the 
      MAE procedure (extraction time, temperature and solvent volume) were optimised 
      using a central composite experimental design combined with desirability 
      functions. The optimal conditions identified were temperature 170 degrees C, 
      solvent volume 35 mL and extraction time 90 min. MAE extracts were concentrated 
      and derivatised prior to separation and quantification by gas chromatography with 
      electron capture detection. To evaluate the applicability of the proposed MAE 
      method, recovery results were compared with those obtained with the Soxhlet 
      extraction method; the results were similar with both extraction methods. The new 
      method was also satisfactorily applied to real cork stopper samples.
FAU - Pizarro, C
AU  - Pizarro C
AD  - Department of Chemistry, University of La Rioja, C/Madre de Dios 51, 26006 
      Logrono, La Rioja, Spain. consuelo.pizarro@dq.unirioja.es 
      <consuelo.pizarro@dq.unirioja.es>
FAU - Perez-del-Notario, N
AU  - Perez-del-Notario N
FAU - Gonzalez-Saiz, J M
AU  - Gonzalez-Saiz JM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20070319
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Anisoles)
RN  - 0 (Halogens)
RN  - 0 (Phenols)
SB  - IM
MH  - Anisoles/*analysis
MH  - Halogens/*analysis
MH  - *Microwaves
MH  - Phellodendron/*chemistry
MH  - Phenols/*analysis
MH  - Reference Standards
EDAT- 2007/03/28 09:00
MHDA- 2007/06/22 09:00
CRDT- 2007/03/28 09:00
PHST- 2007/01/25 00:00 [received]
PHST- 2007/03/07 00:00 [revised]
PHST- 2007/03/09 00:00 [accepted]
PHST- 2007/03/28 09:00 [pubmed]
PHST- 2007/06/22 09:00 [medline]
PHST- 2007/03/28 09:00 [entrez]
AID - S0021-9673(07)00495-5 [pii]
AID - 10.1016/j.chroma.2007.03.055 [doi]
PST - ppublish
SO  - J Chromatogr A. 2007 May 18;1149(2):138-44. doi: 10.1016/j.chroma.2007.03.055. 
      Epub 2007 Mar 19.