PMID- 17400061
OWN - NLM
STAT- MEDLINE
DCOM- 20071126
LR  - 20111117
IS  - 0198-8859 (Print)
IS  - 0198-8859 (Linking)
VI  - 68
IP  - 4
DP  - 2007 Apr
TI  - Implication of HLA-G in human embryo implantation.
PG  - 259-63
AB  - The mechanisms underlying the processes of human embryo implantation and maternal 
      immunotolerance to the fetus remain incompletely understood. Growing evidence 
      indicates that one of the nonclassic human leukocyte antigen (HLA) genes, HLA-G, 
      is expressed selectively on the surface of the extravillous throphoblast and 
      plays an important role in the adaptations of the maternal immune system to 
      pregnancy; however the implication of this molecule in the process of human 
      embryo implantation is also plausible. Therefore the aim of the present article 
      is to review the available literature specifically focused on the possible 
      relationship between HLA-G and human embryo implantation. In particular, studies 
      investigating HLA-G expression on human preimplantation embryos and in the 
      endometrium, as well as its levels in embryo culture supernatants and circulating 
      maternal blood, are discussed.
FAU - Fanchin, Renato
AU  - Fanchin R
AD  - Department of Obstetrics and Gynecology, Hopital Antoine Beclere, Clamart, 
      France. renato.fanchin@abc.ap-hop-paris.fr
FAU - Gallot, Vanessa
AU  - Gallot V
FAU - Rouas-Freiss, Nathalie
AU  - Rouas-Freiss N
FAU - Frydman, Rene
AU  - Frydman R
FAU - Carosella, Edgardo D
AU  - Carosella ED
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20070110
PL  - United States
TA  - Hum Immunol
JT  - Human immunology
JID - 8010936
RN  - 0 (HLA Antigens)
RN  - 0 (HLA-G Antigens)
RN  - 0 (Histocompatibility Antigens Class I)
SB  - IM
MH  - Blastocyst/*immunology
MH  - Embryo Implantation/*immunology
MH  - Female
MH  - HLA Antigens/*physiology
MH  - HLA-G Antigens
MH  - Histocompatibility Antigens Class I/*physiology
MH  - Humans
MH  - Pregnancy
RF  - 48
EDAT- 2007/04/03 09:00
MHDA- 2007/12/06 09:00
CRDT- 2007/04/03 09:00
PHST- 2006/09/15 00:00 [received]
PHST- 2006/11/10 00:00 [revised]
PHST- 2006/11/20 00:00 [accepted]
PHST- 2007/04/03 09:00 [pubmed]
PHST- 2007/12/06 09:00 [medline]
PHST- 2007/04/03 09:00 [entrez]
AID - S0198-8859(06)00595-7 [pii]
AID - 10.1016/j.humimm.2006.11.002 [doi]
PST - ppublish
SO  - Hum Immunol. 2007 Apr;68(4):259-63. doi: 10.1016/j.humimm.2006.11.002. Epub 2007 
      Jan 10.