PMID- 17401755
OWN - NLM
STAT- MEDLINE
DCOM- 20070516
LR  - 20151119
IS  - 0340-9937 (Print)
IS  - 0340-9937 (Linking)
VI  - 32
IP  - 2
DP  - 2007 Mar
TI  - Significance of late gadolinium enhancement in cardiovascular magnetic resonance 
      imaging (CMR).
PG  - 129-37
AB  - Cardiovascular magnetic resonance imaging (CMR) permits optimal differentiation 
      between normal and diseased myocardium with the use of gadoliniumbased contrast 
      agents and special magnetic resonance pulse sequences. Imaging is performed 10-20 
      min after contrast agent application to produce so-called late gadolinium 
      enhancement (LGE) images which depict diseased myocardium with excellent 
      reproducibility. Areas showing LGE correspond to zones of myocyte necrosis or 
      myocardial fibrosis as shown by comparison with histopathology. Typical patterns 
      of hyperenhancement exist in ischemic heart disease but also in dilated 
      cardiomyopathy, hypertrophic cardiomyopathy and other inflammatory or 
      infiltrative myocardial disease and are described in this article. LGE-CMR is 
      helpful to distinguish advanced ischemic heart disease from nonischemic dilated 
      cardiomyopathy. In ischemic heart disease LGE can also predict the functional 
      recovery after revascularization procedures by directly showing the remaining 
      viable myocardium. LGE may also become useful to predict malignant arrhythmias in 
      patients with ischemic heart disease or nonischemic cardiomyopathy. This may lead 
      in future to an increased role of LGE-CMR as a prognostic tool.
FAU - Vohringer, Matthias
AU  - Vohringer M
AD  - Department of Cardiology and Pulmonology, Robert Bosch Hospital, Stuttgart, 
      Germany.
FAU - Mahrholdt, Heiko
AU  - Mahrholdt H
FAU - Yilmaz, Ali
AU  - Yilmaz A
FAU - Sechtem, Udo
AU  - Sechtem U
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Germany
TA  - Herz
JT  - Herz
JID - 7801231
RN  - 0 (Contrast Media)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Animals
MH  - Cardiomyopathies/*diagnosis
MH  - Contrast Media/administration & dosage
MH  - Gadolinium/*administration & dosage
MH  - Heart Diseases/*diagnosis
MH  - Humans
MH  - Image Enhancement/*methods
MH  - Magnetic Resonance Imaging/*methods
RF  - 60
EDAT- 2007/04/03 09:00
MHDA- 2007/05/17 09:00
CRDT- 2007/04/03 09:00
PHST- 2007/04/03 09:00 [pubmed]
PHST- 2007/05/17 09:00 [medline]
PHST- 2007/04/03 09:00 [entrez]
AID - 10.1007/s00059-007-2972-5 [doi]
PST - ppublish
SO  - Herz. 2007 Mar;32(2):129-37. doi: 10.1007/s00059-007-2972-5.