PMID- 17409559
OWN - NLM
STAT- MEDLINE
DCOM- 20070606
LR  - 20190706
IS  - 0009-2363 (Print)
IS  - 0009-2363 (Linking)
VI  - 55
IP  - 4
DP  - 2007 Apr
TI  - Spectrophotometric determination of dopaminergic drugs used for Parkinson's 
      disease, cabergoline and ropinirole, in pharmaceutical preparations.
PG  - 629-31
AB  - Simple and reproducible spectrophotometric methods have been developed for 
      determination of dopaminergic drugs used for Parkinson's disease, cabergoline 
      (CAB) and ropinirole hydrochloride (ROP), in pharmaceutical preparations. The 
      methods are based on the reactions between the studied drug substances and 
      ion-pair agents [methyl orange (MO), bromocresol green (BCG) and bromophenol blue 
      (BPB)] producing yellow colored ion-pair complexes in acidic buffers, after 
      extracting in dichloromethane, which are spectrophotometrically determined at the 
      appropriate wavelength of ion-pair complexes. Beer's law was obeyed within the 
      concentration range from 1.0 to 35 microg ml(-1). The developed methods were 
      applied successfully for the determination of these drugs in tablets.
FAU - Onal, Armagan
AU  - Onal A
AD  - Istanbul University, Faculty of Pharmacy, Department of Analytical Chemistry, 
      Istanbul, Turkey. armaganozkul@yahoo.com
FAU - Caglar, Sena
AU  - Caglar S
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Chem Pharm Bull (Tokyo)
JT  - Chemical & pharmaceutical bulletin
JID - 0377775
RN  - 0 (Dopamine Agents)
RN  - 0 (Ergolines)
RN  - 0 (Indoles)
RN  - 0 (Pharmaceutical Preparations)
RN  - 030PYR8953 (ropinirole)
RN  - LL60K9J05T (Cabergoline)
SB  - IM
MH  - Cabergoline
MH  - Dopamine Agents/*analysis/therapeutic use
MH  - Ergolines/*analysis/therapeutic use
MH  - Humans
MH  - Hydrogen-Ion Concentration
MH  - Indoles/*analysis/therapeutic use
MH  - Parkinson Disease/*drug therapy
MH  - Pharmaceutical Preparations/*chemistry
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
EDAT- 2007/04/06 09:00
MHDA- 2007/06/07 09:00
CRDT- 2007/04/06 09:00
PHST- 2007/04/06 09:00 [pubmed]
PHST- 2007/06/07 09:00 [medline]
PHST- 2007/04/06 09:00 [entrez]
AID - JST.JSTAGE/cpb/55.629 [pii]
AID - 10.1248/cpb.55.629 [doi]
PST - ppublish
SO  - Chem Pharm Bull (Tokyo). 2007 Apr;55(4):629-31. doi: 10.1248/cpb.55.629.