PMID- 17412626 OWN - NLM STAT- MEDLINE DCOM- 20070801 LR - 20070605 IS - 1095-6433 (Print) IS - 1095-6433 (Linking) VI - 147 IP - 4 DP - 2007 Aug TI - Different fatty acid composition in central and peripheral adipose tissues of the American mink (Mustela vison). PG - 903-10 AB - Fatty acid (FA) composition in the intraabdominal (IAB), subcutaneous (SC) and peripheral adipose tissues of the semiaquatic American mink (Mustela vison) was examined in comparison to the diet by gas-liquid chromatography. There was a clear compositional gradient from the IAB via SC to peripheral adipose tissues and the anatomically different adipose tissues accumulated or metabolized FA selectively. The total lipids of the body appendages had smaller proportions of saturated (SFA) and larger proportions of monounsaturated (MUFA) and polyunsaturated fatty acids (PUFA) than the lipids of the trunk adipose tissues. Especially n-3 PUFA were enriched in the periphery. The appendages were also characterized with a high ratio of unsaturated FA to SFA, an increased Delta9-desaturation index and increased mean numbers of double bonds and carbon atoms in a FA molecule. The proportions of SFA and MUFA of the diet resembled the trunk adipose tissues while the dietary percentage of n-3 PUFA surpassed those of the trunk fat depots but was lower than those of the peripheral fats. These data confirm that the FA signatures of mammals reflect not only their dietary history but also metabolic modifications of ingested FA. FAU - Mustonen, Anne-Mari AU - Mustonen AM AD - Faculty of Biosciences, University of Joensuu, P.O. Box 111, FIN-80101, Joensuu, Finland. ammusto@cc.joensuu.fi FAU - Kakela, Reijo AU - Kakela R FAU - Nieminen, Petteri AU - Nieminen P LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20070303 PL - United States TA - Comp Biochem Physiol A Mol Integr Physiol JT - Comparative biochemistry and physiology. Part A, Molecular & integrative physiology JID - 9806096 RN - 0 (Fatty Acids) RN - 0 (Fatty Acids, Unsaturated) SB - IM MH - Adipose Tissue/*chemistry MH - Animals MH - Diet MH - Fatty Acids/*analysis MH - Fatty Acids, Unsaturated/analysis MH - Female MH - Mink/*metabolism MH - Principal Component Analysis EDAT- 2007/04/07 09:00 MHDA- 2007/08/02 09:00 CRDT- 2007/04/07 09:00 PHST- 2006/09/12 00:00 [received] PHST- 2006/12/19 00:00 [revised] PHST- 2007/02/16 00:00 [accepted] PHST- 2007/04/07 09:00 [pubmed] PHST- 2007/08/02 09:00 [medline] PHST- 2007/04/07 09:00 [entrez] AID - S1095-6433(07)00871-9 [pii] AID - 10.1016/j.cbpa.2007.02.021 [doi] PST - ppublish SO - Comp Biochem Physiol A Mol Integr Physiol. 2007 Aug;147(4):903-10. doi: 10.1016/j.cbpa.2007.02.021. Epub 2007 Mar 3.