PMID- 17417905
OWN - NLM
STAT- MEDLINE
DCOM- 20070816
LR  - 20131121
IS  - 1525-7797 (Print)
IS  - 1525-7797 (Linking)
VI  - 8
IP  - 5
DP  - 2007 May
TI  - Cationic amphiphilic model networks based on symmetrical ABCBA pentablock 
      terpolymers: synthesis, characterization, and modeling.
PG  - 1615-23
AB  - Eight isomeric networks based on equimolar terpolymers were synthesized using 
      group transfer polymerization (GTP) and were characterized in terms of their 
      swelling properties. Two hydrophilic monomers, the nonionic methoxy hexa(ethylene 
      glycol) methacrylate (HEGMA) and the ionizable 2-(dimethylamino)ethyl 
      methacrylate (DMAEMA), and a hydrophobic (nonionic) monomer, methyl methacrylate 
      (MMA), were employed for the syntheses. 
      1,4-Bis(methoxytrimethylsiloxymethylene)cyclohexane (MTSMC) was used as the 
      bifunctional GTP initiator, while ethylene glycol dimethacrylate (EGDMA) served 
      as the cross-linker. Seven of the networks were model networks, six of which were 
      based on the symmetrical pentablock terpolymers ABCBA, ACBCA, BACAB, BCACB, 
      CBABC, and CABAC, whereas the seventh model network was based on the statistical 
      terpolymer. The eighth network was a randomly cross-linked network based on the 
      statistical terpolymer, prepared by the simultaneous quaterpolymerization of the 
      three monomers and the cross-linker. The molecular weights and molecular weight 
      distributions of the linear pentablock terpolymer precursors, as well as those of 
      their homopolymer and ABA triblock copolymer precursors, were characterized by 
      gel permeation chromatography (GPC) in tetrahydrofuran. The sol fraction of each 
      network was measured and found to be relatively low. The aqueous degrees of 
      swelling of all networks were found to increase at acidic pH due to the 
      ionization of the DMAEMA tertiary amine units. The acidic degrees of swelling of 
      the pentablock terpolymer networks were lower than those of their statistical 
      counterparts due to microphase separation in the former type of networks, also 
      confirmed by thermodynamic calculations and small-angle neutron scattering 
      experiments.
FAU - Triftaridou, Aggeliki I
AU  - Triftaridou AI
AD  - Department of Chemistry, University of Cyprus, P. O. Box 20537, 1678 Nicosia, 
      Cyprus.
FAU - Vamvakaki, Maria
AU  - Vamvakaki M
FAU - Patrickios, Costas S
AU  - Patrickios CS
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20070407
PL  - United States
TA  - Biomacromolecules
JT  - Biomacromolecules
JID - 100892849
RN  - 0 (Cations)
RN  - 0 (Ethylene Glycols)
RN  - 0 (Methacrylates)
RN  - 0 (Polymers)
RN  - 0 (hydrophilic methoxy hexa(ethylene glycol) methacrylate)
RN  - 059QF0KO0R (Water)
RN  - 196OC77688 (Methylmethacrylate)
RN  - O0V97PV2G1 (2-(dimethylamino)ethyl methacrylate)
SB  - IM
MH  - Cations/chemistry
MH  - Ethylene Glycols/*chemistry
MH  - Methacrylates/*chemistry
MH  - Methylmethacrylate/*chemistry
MH  - *Models, Chemical
MH  - Molecular Weight
MH  - Polymers/*chemical synthesis/chemistry
MH  - Thermodynamics
MH  - Water/chemistry
EDAT- 2007/04/10 09:00
MHDA- 2007/08/19 09:00
CRDT- 2007/04/10 09:00
PHST- 2007/04/10 09:00 [pubmed]
PHST- 2007/08/19 09:00 [medline]
PHST- 2007/04/10 09:00 [entrez]
AID - 10.1021/bm0611477 [doi]
PST - ppublish
SO  - Biomacromolecules. 2007 May;8(5):1615-23. doi: 10.1021/bm0611477. Epub 2007 Apr 
      7.