PMID- 17431324
OWN - NLM
STAT- MEDLINE
DCOM- 20070430
LR  - 20070413
IS  - 1424-859X (Electronic)
IS  - 1424-8581 (Linking)
VI  - 116
IP  - 4
DP  - 2007
TI  - Karyotype, centric fusion polymorphism and chromosomal aberrations in 
      captive-born mountain reedbuck (Redunca fulvorufula).
PG  - 263-8
AB  - Chromosomes of fourteen captive-born mountain reedbucks (Redunca fulvorufula) 
      have been investigated. The diploid chromosome number was 2n = 56 (FN = 60). The 
      mountain reedbuck karyotype consists of 26 acrocentric and two biarmed chromosome 
      pairs resulting from two centric fusions involving chromosomes 2 and 25, and 6 
      and 10, respectively. In some animals, 57 chromosomes were detected. Variation in 
      the diploid number was found to be due to polymorphism for the centric fusion 
      6;10. Both X and Y chromosomes are large and acrocentric. The entire Y chromosome 
      and the proximal part of the X chromosome consist of heterochromatin. The 
      chromosomes X, 9 and 14 appeared to be of caprine type. Chromosome aberrations 
      have been detected in two of the 14 animals investigated. A de novo formed 
      Robertsonian translocation rob(6;13) was found in one female heterozygous for the 
      fusion 6;10. CBG-banding revealed one block of centromeric heterochromatin in the 
      de novo formed translocation rob(6;13) and also in the evolutionarily fixed 
      centric fusions 6;10 and 2;25. One examined male homozygous for fusion 6;10, had 
      a mosaic 56,XY/57,XYY karyotype, with 11% of analyzed cells containing two Y 
      chromosomes. The findings were confirmed by cross-species fluorescence in situ 
      hybridization (FISH) with bovine (Bos taurus L.) chromosome painting probes. The 
      study demonstrates the relevance of cytogenetic screening in captive animals from 
      zoological gardens.
CI  - Copyright 2007 S. Karger AG, Basel.
FAU - Rubes, J
AU  - Rubes J
AD  - Veterinary Research Institute, Brno, Czech Republic. rubes@vri.cz
FAU - Pagacova, E
AU  - Pagacova E
FAU - Kopecna, O
AU  - Kopecna O
FAU - Kubickova, S
AU  - Kubickova S
FAU - Cernohorska, H
AU  - Cernohorska H
FAU - Vahala, J
AU  - Vahala J
FAU - Di Berardino, D
AU  - Di Berardino D
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Switzerland
TA  - Cytogenet Genome Res
JT  - Cytogenetic and genome research
JID - 101142708
SB  - IM
MH  - Animals
MH  - Centromere/*genetics
MH  - *Chromosome Aberrations
MH  - Chromosome Banding
MH  - Female
MH  - Heterozygote
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Male
MH  - Metaphase
MH  - Pedigree
MH  - *Polymorphism, Genetic
MH  - Ruminants/*genetics
MH  - X Chromosome/genetics/metabolism
EDAT- 2007/04/14 09:00
MHDA- 2007/05/01 09:00
CRDT- 2007/04/14 09:00
PHST- 2006/07/17 00:00 [received]
PHST- 2006/11/14 00:00 [accepted]
PHST- 2007/04/14 09:00 [pubmed]
PHST- 2007/05/01 09:00 [medline]
PHST- 2007/04/14 09:00 [entrez]
AID - 000100410 [pii]
AID - 10.1159/000100410 [doi]
PST - ppublish
SO  - Cytogenet Genome Res. 2007;116(4):263-8. doi: 10.1159/000100410.