PMID- 17433003 OWN - NLM STAT- MEDLINE DCOM- 20070626 LR - 20220317 IS - 0905-6157 (Print) IS - 0905-6157 (Linking) VI - 18 IP - 3 DP - 2007 May TI - Efficacy of donkey's milk in treating highly problematic cow's milk allergic children: an in vivo and in vitro study. PG - 258-64 AB - Successful therapy in cow's milk protein allergy rests on completely eliminating cow's milk proteins from the child's diet: it is thus necessary to provide a replacement food. This prospective study investigated tolerance of donkey's milk in a population of 46 selected children with cow's milk protein allergy, for whom it was not possible to use any cow's milk substitute. Thirty-eight children (82.6%) liked and tolerated donkey's milk at the challenge and for the entire duration of follow-up. Catch-up growth was observed in all subjects with growth deficit during cow's milk proteins challenge. The degree of cross-reactivity of immunoglobulin E (IgE) with donkey's milk proteins was very weak and aspecific. Donkey's milk was found to be a valid alternative to both IgE-mediated and non-IgE-mediated cow's milk proteins allergy, including in terms of palatability and weight-height gain. FAU - Monti, Giovanna AU - Monti G AD - Department of Paediatric and Adolescence Science, Regina Margherita Children's Hospital, Turin, Italy. FAU - Bertino, Enrico AU - Bertino E FAU - Muratore, Maria Cristina AU - Muratore MC FAU - Coscia, Alessandra AU - Coscia A FAU - Cresi, Francesco AU - Cresi F FAU - Silvestro, Leandra AU - Silvestro L FAU - Fabris, Claudio AU - Fabris C FAU - Fortunato, Donatella AU - Fortunato D FAU - Giuffrida, Maria Gabriella AU - Giuffrida MG FAU - Conti, Amedeo AU - Conti A LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Pediatr Allergy Immunol JT - Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology JID - 9106718 SB - IM CIN - Pediatr Allergy Immunol. 2007 Nov;18(7):625-6. PMID: 18001434 MH - Adolescent MH - Animals MH - Child MH - Child, Preschool MH - Equidae MH - Female MH - Humans MH - In Vitro Techniques MH - Infant MH - Italy MH - Male MH - *Milk/adverse effects MH - Milk Hypersensitivity/*diet therapy/etiology MH - Prospective Studies MH - Treatment Outcome EDAT- 2007/04/17 09:00 MHDA- 2007/06/27 09:00 CRDT- 2007/04/17 09:00 PHST- 2007/04/17 09:00 [pubmed] PHST- 2007/06/27 09:00 [medline] PHST- 2007/04/17 09:00 [entrez] AID - PAI521 [pii] AID - 10.1111/j.1399-3038.2007.00521.x [doi] PST - ppublish SO - Pediatr Allergy Immunol. 2007 May;18(3):258-64. doi: 10.1111/j.1399-3038.2007.00521.x.