PMID- 17437061
OWN - NLM
STAT- MEDLINE
DCOM- 20070917
LR  - 20220716
IS  - 0165-5701 (Print)
IS  - 0165-5701 (Linking)
VI  - 27
IP  - 2-3
DP  - 2007 Apr-Jun
TI  - Vogt-Koyanagi-Harada disease in elderly Japanese patients.
PG  - 149-53
AB  - PURPOSE: The purpose of this study was to evaluate the characteristics of 
      Vogt-Koyanagi-Harada (VKH) disease in elderly (age > or =65 years) Japanese 
      patients. METHODS: We reviewed the medical records of all patients diagnosed with 
      VKH disease at the Department of Ophthalmology, Oita University Hospital between 
      October 1982 and March 2005. Data extracted included age, gender, prodromal 
      symptoms, visual acuity, ocular manifestations, extraocular findings, human 
      leukocyte antigen (HLA), ocular complications, treatment, and smoldering 
      inflammation. RESULTS: Of the 68 patients with VKH disease, seven (10%) were 
      classified as elderly at onset. The incidence of optic disk hyperemia, choroidal 
      detachment, and cataract was significantly higher in the elderly patients than 
      the non-elderly patients (<65 years). The total dose of corticosteroid used was 
      higher in the elderly. The incidence of smoldering inflammation was more frequent 
      in the elderly. Final visual acuity was preserved relatively well in the elderly. 
      CONCLUSION: The significantly higher incidence of optic disk hyperemia, choroidal 
      detachment, and cataract, and the more frequent smoldering inflammation in 
      elderly VKH patients indicate that special attention should be paid to these 
      parameters in elderly patients.
FAU - Kiyomoto, Chihiro
AU  - Kiyomoto C
AD  - Department of Ophthalmology, Oita University, Faculty of Medicine, 1-1 Idaigaoka, 
      Hasama-machi, Yufu, Oita 879-5593, Japan.
FAU - Imaizumi, Masamoto
AU  - Imaizumi M
FAU - Kimoto, Kenichi
AU  - Kimoto K
FAU - Abe, Hiromi
AU  - Abe H
FAU - Nakano, Satoko
AU  - Nakano S
FAU - Nakatsuka, Kazuo
AU  - Nakatsuka K
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20070414
PL  - Netherlands
TA  - Int Ophthalmol
JT  - International ophthalmology
JID - 7904294
RN  - 0 (Glucocorticoids)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age of Onset
MH  - Aged
MH  - Choroid Diseases/diagnosis
MH  - Female
MH  - Glucocorticoids/administration & dosage
MH  - Humans
MH  - Hyperemia/diagnosis
MH  - Japan/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Optic Disk/blood supply
MH  - Uveomeningoencephalitic Syndrome/diagnosis/drug therapy/*epidemiology
MH  - Visual Acuity
EDAT- 2007/04/18 09:00
MHDA- 2007/09/18 09:00
CRDT- 2007/04/18 09:00
PHST- 2007/01/25 00:00 [received]
PHST- 2007/02/25 00:00 [accepted]
PHST- 2007/04/18 09:00 [pubmed]
PHST- 2007/09/18 09:00 [medline]
PHST- 2007/04/18 09:00 [entrez]
AID - 10.1007/s10792-007-9067-4 [doi]
PST - ppublish
SO  - Int Ophthalmol. 2007 Apr-Jun;27(2-3):149-53. doi: 10.1007/s10792-007-9067-4. Epub 
      2007 Apr 14.