PMID- 17437221
OWN - NLM
STAT- MEDLINE
DCOM- 20070705
LR  - 20070417
IS  - 1476-7058 (Print)
IS  - 1476-4954 (Linking)
VI  - 20
IP  - 3
DP  - 2007 Mar
TI  - Effect of maternal congenital heart defects on labor and delivery outcome: a 
      population-based study.
PG  - 211-6
AB  - OBJECTIVE: The primary objective of this study was to characterize the delivery 
      outcome of parturients with congenital heart defects (CHD), from maternal and 
      from neonatal perspectives. STUDY DESIGN: A retrospective population-based study 
      was conducted, covering a 13-year period (1989-2002) with an aggregate of 151,487 
      deliveries of all women with and without CHD. Maternal demographics, obstetrical 
      and medical history, delivery outcome, and neonatal outcome were drawn from a 
      computerized perinatal database. RESULTS: Sixty-seven women with CHD had 156 
      deliveries. The severity of CHD, based on the New York Heart Association (NYHA) 
      classification, was I or II in 99.1% of the deliveries. CHD patients had 
      significantly higher rates of labor induction and neonatal malformations. 
      Maternal CHD was discovered as an independent risk factor associated with 
      neonatal malformations (OR 2.10, 95% CI 1.18-3.72). No significant differences 
      were noted between women with CHD and the controls regarding maternal morbidities 
      and Apgar scores. CONCLUSIONS: The labor outcome of CHD patients with NYHA 
      classification I and II resembles that of non-CHD women in a tertiary center 
      setting. Neonates of CHD mothers have higher rates of congenital malformations 
      even among asymptomatic or mildly symptomatic mothers. A careful sonographic 
      follow-up is warranted among all pregnancies of CHD patients.
FAU - Sidlik, Rakefet
AU  - Sidlik R
AD  - Department of Obstetrics & Gynecology, Faculty of Health Services, Soroka 
      University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, 
      Israel.
FAU - Sheiner, Eyal
AU  - Sheiner E
FAU - Levy, Amalia
AU  - Levy A
FAU - Wiznitzer, Arnon
AU  - Wiznitzer A
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Matern Fetal Neonatal Med
JT  - The journal of maternal-fetal & neonatal medicine : the official journal of the 
      European Association of Perinatal Medicine, the Federation of Asia and Oceania 
      Perinatal Societies, the International Society of Perinatal Obstetricians
JID - 101136916
SB  - IM
MH  - Adult
MH  - Female
MH  - Heart Defects, Congenital/*complications/epidemiology
MH  - Humans
MH  - Multivariate Analysis
MH  - Obstetric Labor Complications/*epidemiology
MH  - Parity
MH  - Pregnancy
MH  - Pregnancy Complications, Cardiovascular/*epidemiology
MH  - Pregnancy Outcome/*epidemiology
MH  - Retrospective Studies
EDAT- 2007/04/18 09:00
MHDA- 2007/07/06 09:00
CRDT- 2007/04/18 09:00
PHST- 2007/04/18 09:00 [pubmed]
PHST- 2007/07/06 09:00 [medline]
PHST- 2007/04/18 09:00 [entrez]
AID - 771300069 [pii]
AID - 10.1080/14767050600923980 [doi]
PST - ppublish
SO  - J Matern Fetal Neonatal Med. 2007 Mar;20(3):211-6. doi: 
      10.1080/14767050600923980.