PMID- 17438246
OWN - NLM
STAT- MEDLINE
DCOM- 20070515
LR  - 20161124
IS  - 0886-4470 (Print)
IS  - 0886-4470 (Linking)
VI  - 133
IP  - 4
DP  - 2007 Apr
TI  - A new clinical olfactory function test: cross-cultural influence.
PG  - 331-6
AB  - OBJECTIVE: To investigate whether a new clinical olfactory test, the Odor Stick 
      Identification Test for Japanese (OSIT-J), can be used to assess olfactory 
      function cross-culturally in a US patient population. DESIGN: Cross-sectional 
      prospective study. SETTING: A university medical center otolaryngology clinic. 
      PATIENTS: Fifty US patients presenting with complaints of olfactory dysfunction 
      from December 2004 to January 2006. INTERVENTIONS: Olfactory testing and patient 
      interview. MAIN OUTCOME MEASURES: Comparison of test results obtained with the 
      OSIT-J, the Connecticut Chemosensory Clinical Research Center (CCCRC) olfactory 
      function test, and patients' self-reported level of olfactory function. Patients' 
      opinions regarding the 2 test methods were also recorded. RESULTS: The mean +/- 
      SD time required to administer the OSIT-J (8 +/- 1 minutes) was shorter than that 
      required for the standard CCCRC test (21 +/- 6 minutes). Significant Spearman 
      rank correlations were found between the OSIT-J and CCCRC test scores (r(s) = 
      0.80, P<.001, n = 50), and patients' self-reported level of olfactory function 
      (r(s) = 0.73, P<.001, n = 50). Although 3 of the 13 odors used in the OSIT-J were 
      not familiar to US subjects, patients reported that the OSIT-J was easier, more 
      interesting, and the odors used more pleasant than the CCCRC test. CONCLUSIONS: 
      Olfactory function tests developed in different countries should be evaluated to 
      determine if a cross-cultural bias exists among test odorants. Although a 
      cultural bias was detected for a few odorants, this study demonstrates that a 
      modified version of the OSIT-J can be used to assess olfactory function in US 
      patients.
FAU - Kobayashi, Masayoshi
AU  - Kobayashi M
AD  - Department of Physiology, Virginia Commonwealth University School of Medicine, 
      Richmond, USA. m-koba@doc.medic.mie-u.ac.jp
FAU - Reiter, Evan R
AU  - Reiter ER
FAU - DiNardo, Laurence J
AU  - DiNardo LJ
FAU - Costanzo, Richard M
AU  - Costanzo RM
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Arch Otolaryngol Head Neck Surg
JT  - Archives of otolaryngology--head & neck surgery
JID - 8603209
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Chi-Square Distribution
MH  - *Cross-Cultural Comparison
MH  - Cross-Sectional Studies
MH  - Data Interpretation, Statistical
MH  - Female
MH  - Humans
MH  - Japan
MH  - Male
MH  - Middle Aged
MH  - *Odorants
MH  - Olfaction Disorders/*diagnosis
MH  - Prospective Studies
MH  - Sensitivity and Specificity
MH  - Smell/*physiology
MH  - Statistics, Nonparametric
MH  - United States
EDAT- 2007/04/18 09:00
MHDA- 2007/05/16 09:00
CRDT- 2007/04/18 09:00
PHST- 2007/04/18 09:00 [pubmed]
PHST- 2007/05/16 09:00 [medline]
PHST- 2007/04/18 09:00 [entrez]
AID - 133/4/331 [pii]
AID - 10.1001/archotol.133.4.331 [doi]
PST - ppublish
SO  - Arch Otolaryngol Head Neck Surg. 2007 Apr;133(4):331-6. doi: 
      10.1001/archotol.133.4.331.