PMID- 17441368
OWN - NLM
STAT- MEDLINE
DCOM- 20070717
LR  - 20161124
IS  - 0033-2240 (Print)
IS  - 0033-2240 (Linking)
VI  - 63
IP  - 8
DP  - 2006
TI  - [Vascular abnormalities in patients with primary intracerebral hemorrhage].
PG  - 616-9
AB  - BACKGROUND: To prevent the recurrence of primary intracerebral hemorrhage (PIH) 
      it is important to identify patients with underlying structural vascular 
      abnormalities (VA). According to previous study data-- the site of hemorrhage, 
      the patient's age and pre-existing hypertension affect the likelihood of finding 
      VA. However, the indications for angiography, the gold standard for the diagnosis 
      of VA, still remain controversial. PURPOSE: To assess the frequency of VA and to 
      determine features that might increase the probability of finding VA in patients 
      with PIH. MATERIAL AND METHODS: 100 patients with PIH, without a history of 
      trauma, coagulopathy, or known pre-existing brain abnormality, who were admitted 
      to the Stroke Unit of the Department of Neurology, Jagiellonian University, 
      between January 1999 and November 2000 entered this prospectively designed study. 
      In the group of 96 patients, 53 persons underwent conventional angiography within 
      14 days of stroke onset (in 4 cases we found bleeding into the tumor and these 
      patients were not included in further analysis). RESULTS: Vascular abnormalities 
      were found in 14 of 53 patients (26.4%); ruptured aneurysms in 9 patients 
      (17.0%), arteriovenous malformations (AVM) in 3 patients (5.7%), venous angioma 
      in 1 patient (1.8%) and cavernous angioma in 1 patient (1.9%). Vascular 
      malformations were found in 12 of 25 patients with lobar hemorrhage, in 1 of 8 
      patients with hemorrhage originating in the thalamus and in 1 of 2 patients with 
      hemorrhage originating in the pons. Angiographic findings were negative in 8 
      patients with hemorrhage in the periventricular white matter, in 8 with 
      hemorrhage originating in the basal ganglia and in 2 patients with hemorrhage in 
      the cerebellum. Patients with VA were significantly younger than patients without 
      VA (49.9 +/- 11.7 years and 58.7 +/- 13.3 years respectively, p = 0.03) and they 
      had a history of hypertension significantly less often (50.0% and 89.7%, p = 
      0.001). Intraventricular hemorrhage and subarachnoid bleeding occurred in a 
      similar percentage of patients with ICH, independent of whether or not they had 
      VA (28.6% and 38.5%; 21.4% and 10.3% respectively, p = n.s.). CONCLUSIONS: (1) A 
      vascular abnormality is the cause of about 26% of ICH, with a higher likelihood 
      in younger patients and with lobar hemorrhage. (2) A history of hypertension does 
      not exclude the presence of VA. (3) Intraventricular hemorrhage or subarachnoid 
      bleeding does not predict the presence of VA.
FAU - Slowik, Agnieszka
AU  - Slowik A
AD  - Klinika Neurologii Collegium Medicum, Uniwersytetu Jagiellonskiego w Krakowie. 
      slowik@cm-uj.krakow.pl
FAU - Szermer, Pawel
AU  - Szermer P
FAU - Turaj, Wojciech
AU  - Turaj W
FAU - Glodzik-Sobanska, Lidia
AU  - Glodzik-Sobanska L
FAU - Dziedzic, Tomasz
AU  - Dziedzic T
FAU - Pera, Joanna
AU  - Pera J
FAU - Brys, Miroslaw
AU  - Brys M
FAU - Uhl, Henryka
AU  - Uhl H
FAU - Szczudlik, Andrzej
AU  - Szczudlik A
LA  - pol
PT  - Journal Article
TT  - Malformacje naczyn mozgowych u chorych z pierwotnym krwotokiem srodmozgowym.
PL  - Poland
TA  - Przegl Lek
JT  - Przeglad lekarski
JID - 19840720R
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cerebral Angiography
MH  - Cerebral Hemorrhage/*diagnostic imaging/*etiology/surgery
MH  - Female
MH  - Humans
MH  - Intracranial Aneurysm/complications/diagnostic imaging
MH  - Intracranial Arteriovenous Malformations/*complications/*diagnostic 
      imaging/surgery
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Tomography, X-Ray Computed
EDAT- 2007/04/20 09:00
MHDA- 2007/07/18 09:00
CRDT- 2007/04/20 09:00
PHST- 2007/04/20 09:00 [pubmed]
PHST- 2007/07/18 09:00 [medline]
PHST- 2007/04/20 09:00 [entrez]
PST - ppublish
SO  - Przegl Lek. 2006;63(8):616-9.