PMID- 17443046
OWN - NLM
STAT- MEDLINE
DCOM- 20070614
LR  - 20190606
IS  - 1349-7235 (Electronic)
IS  - 0918-2918 (Linking)
VI  - 46
IP  - 8
DP  - 2007
TI  - Slowly progressive distal muscular atrophy of the bilateral upper limbs 
      (O'Sullivan-McLeod syndrome) partially alleviated by intravenous immunoglobulin 
      therapy.
PG  - 515-8
AB  - We report a case of O'Sullivan-McLeod syndrome in a 59-year-old man, who had 
      experienced slowly progressive weakening of both hands since he was 20 years of 
      age. Mild hyperIgEemia and eosinophilia were present. Nerve conduction studies 
      revealed reduced F wave-evoked frequencies for the median and ulnar nerves. 
      Intravenous immunoglobulin (IVIG) at a dose of 400 mg/kg/day was given for 5 
      days. After IVIG, the muscle weakness of the distal upper extremities improved 
      together with increased F wave-evoked frequencies. These effects lasted for a few 
      months. These observations suggest that immune-mediated neural damage partially 
      contributes to O'Sullivan-McLeod syndrome.
FAU - Kawano, Yuji
AU  - Kawano Y
AD  - Department of Neurology, Neurological Institute, Graduate School of Medical 
      Sciences, Kyushu University, Fukuoka.
FAU - Nagara, Yuko
AU  - Nagara Y
FAU - Murai, Hiroyuki
AU  - Murai H
FAU - Kikuchi, Hitoshi
AU  - Kikuchi H
FAU - Ohyagi, Yasumasa
AU  - Ohyagi Y
FAU - Kira, Jun-ichi
AU  - Kira J
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20070417
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
RN  - 0 (Immunoglobulins, Intravenous)
SB  - IM
MH  - Arm/*diagnostic imaging
MH  - Disease Progression
MH  - Humans
MH  - Immunoglobulins, Intravenous/*therapeutic use
MH  - Male
MH  - Middle Aged
MH  - Muscular Atrophy/*diagnostic imaging/*drug therapy
MH  - Radiography
MH  - Syndrome
EDAT- 2007/04/20 09:00
MHDA- 2007/06/15 09:00
CRDT- 2007/04/20 09:00
PHST- 2007/04/20 09:00 [pubmed]
PHST- 2007/06/15 09:00 [medline]
PHST- 2007/04/20 09:00 [entrez]
AID - JST.JSTAGE/internalmedicine/46.6221 [pii]
AID - 10.2169/internalmedicine.46.6221 [doi]
PST - ppublish
SO  - Intern Med. 2007;46(8):515-8. doi: 10.2169/internalmedicine.46.6221. Epub 2007 
      Apr 17.