PMID- 17445155
OWN - NLM
STAT- MEDLINE
DCOM- 20070621
LR  - 20070420
IS  - 0001-2815 (Print)
IS  - 0001-2815 (Linking)
VI  - 69 Suppl 1
DP  - 2007 Apr
TI  - Quality control for registry HLA data.
PG  - 13-4
AB  - In this panel discussion, the following issues were addressed: the evaluation of 
      the quality of the volunteer donors human leukocyte antigen (HLA) assignments, 
      the quality criteria that should be met by the laboratories, the source of 
      errors, the measures that registries can take to assess the quality of HLA 
      testing, and the updating of the initial result with emphasis on resolution of 
      typing discrepancies. Several relevant factors were put forward: the need for the 
      registries to define the HLA loci and the level of resolution requested, and the 
      importance of the accreditation programs with adequate external proficiency 
      testing. The feasibility of annual quality controls of a national registry 
      addressing the limitations of HLA class I serology, and the rules set up by a 
      large registry to incorporate new data on donors HLA types and to rapidly track 
      typing discrepancies, were reported.
FAU - Tiercy, J-M
AU  - Tiercy JM
AD  - National Reference Laboratory for Histocompatibility, University Hospital, 
      Geneva, Switzerland. jean-marie.tiercy@medecine.unige.ch
FAU - Fischer, G
AU  - Fischer G
FAU - Setterholm, M
AU  - Setterholm M
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (HLA Antigens)
SB  - IM
MH  - HLA Antigens/*genetics
MH  - Histocompatibility Testing/*standards
MH  - Humans
MH  - *Quality Control
MH  - *Registries
MH  - Tissue Donors
RF  - 0
EDAT- 2007/04/21 09:00
MHDA- 2007/06/22 09:00
CRDT- 2007/04/21 09:00
PHST- 2007/04/21 09:00 [pubmed]
PHST- 2007/06/22 09:00 [medline]
PHST- 2007/04/21 09:00 [entrez]
AID - TAN758_6 [pii]
AID - 10.1111/j.1399-0039.2006.758_6.x [doi]
PST - ppublish
SO  - Tissue Antigens. 2007 Apr;69 Suppl 1:13-4. doi: 10.1111/j.1399-0039.2006.758_6.x.