PMID- 17445159 OWN - NLM STAT- MEDLINE DCOM- 20070621 LR - 20081121 IS - 0001-2815 (Print) IS - 0001-2815 (Linking) VI - 69 Suppl 1 DP - 2007 Apr TI - Effect of HLA-A2 allele disparity on clinical outcome in hematopoietic cell transplantation from unrelated donors. PG - 31-5 AB - Population-based differences in clinical outcome after unrelated donor hematopoietic cell transplantation suggest that the significance of human leukocyte antigen (HLA) mismatching may be related to locus-specific and allele-specific differences that distinguish ethnically diverse transplant donors and recipients. We studied the risks associated with HLA-A locus mismatching in two large transplant populations from the International Histocompatibility Working Group in hematopoietic cell transplantation data set to better understand permissible and nonpermissible HLA-A mismatches. FAU - Morishima, Y AU - Morishima Y AD - Aichi Cancer Center, Nagoya, Japan. ymorisim@aichi-cc.jp FAU - Kawase, T AU - Kawase T FAU - Malkki, M AU - Malkki M FAU - Petersdorf, E W AU - Petersdorf EW CN - International Histocompatibility Working Group in Hematopoietic Cell Transplantation Component LA - eng GR - AI069197/AI/NIAID NIH HHS/United States GR - AI33484/AI/NIAID NIH HHS/United States GR - AI49213/AI/NIAID NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't PT - Research Support, U.S. Gov't, Non-P.H.S. PL - England TA - Tissue Antigens JT - Tissue antigens JID - 0331072 RN - 0 (HLA-A2 Antigen) SB - IM MH - Alleles MH - *Blood Donors MH - Disease-Free Survival MH - Donor Selection MH - *Genetic Variation MH - Graft Survival MH - Graft vs Host Disease/etiology/prevention & control MH - HLA-A2 Antigen/*genetics/*immunology MH - *Hematopoietic Stem Cell Transplantation MH - *Histocompatibility MH - Humans MH - Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics/*therapy MH - Survival Rate MH - Treatment Outcome EDAT- 2007/04/21 09:00 MHDA- 2007/06/22 09:00 CRDT- 2007/04/21 09:00 PHST- 2007/04/21 09:00 [pubmed] PHST- 2007/06/22 09:00 [medline] PHST- 2007/04/21 09:00 [entrez] AID - TAN759_3 [pii] AID - 10.1111/j.1399-0039.2006.759_3.x [doi] PST - ppublish SO - Tissue Antigens. 2007 Apr;69 Suppl 1:31-5. doi: 10.1111/j.1399-0039.2006.759_3.x.