PMID- 17445559 OWN - NLM STAT- MEDLINE DCOM- 20070719 LR - 20220318 IS - 0041-1345 (Print) IS - 0041-1345 (Linking) VI - 39 IP - 3 DP - 2007 Apr TI - Heart transplantation in chile: preliminary report from the Gustavo Fricke hospital in Vina del Mar. PG - 619-21 AB - OBJECTIVE: The aim of this study was to analyze our results as the national reference center of the public health network in Chile. PATIENTS AND METHODS: Retrospective analysis of all transplantations performed between 1998 and 2005 was done and actuarial survival estimates were calculated according to Kaplan-Meier. RESULTS: Heart transplantations were performed in 25 patients of mean age 43 +/- 11.2 years. Eight patients (32%) were transplanted from a national priority list; all patients were under intensive care support with inotropic therapy, 4 were mechanically ventilated, and 1 required an intra-aortic counter pulsation balloon. The average time on the waiting list was 145 days in nonurgent cases and 9.4 days in urgent ones. Perioperative mortality occurred in 1 patient (4%) due to primary graft failure; 2 patients died due to infectious complications during the first year of follow-up; and 1 died due to a non-cytomegalovirus (CMV) infection at 51 months after transplantation. Two patients developed acute rejection with full recovery. The most common morbidities in the current series were hypertension (71%); hyperlipidemia (71%); renal dysfunction (24%); diabetes (10%); and vasculopathy (10%). Actuarial survival rates were 87.2% and 74.7% at 12 and 86 months, respectively. At 7 years follow-up, 20 patients were in New York Heart Association (NYHA) Class I and one Class II. CONCLUSION: Our heart transplantation program showed comparable results in the short and midterm follow-up when compared with other international reports, confirming that heart transplantation is an excellent therapeutic option for patients with end-stage heart failure. FAU - Aranguiz-Santander, E AU - Aranguiz-Santander E AD - Department of Cardiovascular Surgery, Gustavo Fricke Hospital, Vina del Mar, and the University of Valparaiso, Valparaiso, Chile. eransant@hotmail.com FAU - Merello, L AU - Merello L FAU - Pedemonte, O AU - Pedemonte O FAU - Torres, H AU - Torres H FAU - Vera, A AU - Vera A FAU - Alburquerque, J AU - Alburquerque J LA - eng PT - Journal Article PL - United States TA - Transplant Proc JT - Transplantation proceedings JID - 0243532 SB - IM MH - Adult MH - Chile MH - Community Networks MH - Heart Transplantation/mortality/*statistics & numerical data MH - Humans MH - Middle Aged MH - Postoperative Complications/classification MH - Retrospective Studies MH - Survival Analysis MH - Time Factors MH - Treatment Failure MH - Treatment Outcome MH - Waiting Lists EDAT- 2007/04/21 09:00 MHDA- 2007/07/20 09:00 CRDT- 2007/04/21 09:00 PHST- 2007/04/21 09:00 [pubmed] PHST- 2007/07/20 09:00 [medline] PHST- 2007/04/21 09:00 [entrez] AID - S0041-1345(06)01571-5 [pii] AID - 10.1016/j.transproceed.2006.12.024 [doi] PST - ppublish SO - Transplant Proc. 2007 Apr;39(3):619-21. doi: 10.1016/j.transproceed.2006.12.024.