PMID- 17446831 OWN - NLM STAT- MEDLINE DCOM- 20070612 LR - 20220321 IS - 0025-7079 (Print) IS - 0025-7079 (Linking) VI - 45 IP - 5 DP - 2007 May TI - Hospital workload and adverse events. PG - 448-55 AB - CONTEXT: Hospitals are under pressure to increase revenue and lower costs, and at the same time, they face dramatic variation in clinical demand. OBJECTIVE: : We sought to determine the relationship between peak hospital workload and rates of adverse events (AEs). METHODS: A random sample of 24,676 adult patients discharged from the medical/surgical services at 4 US hospitals (2 urban and 2 suburban teaching hospitals) from October 2000 to September 2001 were screened using administrative data, leaving 6841 cases to be reviewed for the presence of AEs. Daily workload for each hospital was characterized by volume, throughput (admissions and discharges), intensity (aggregate DRG weight), and staffing (patient-to-nurse ratios). For volume, we calculated an "enhanced" occupancy rate that accounted for same-day bed occupancy by more than 1 patient. We used Poisson regressions to predict the likelihood of an AE, with control for workload and individual patient complexity, and the effects of clustering. RESULTS: One urban teaching hospital had enhanced occupancy rates more than 100% for much of the year. At that hospital, admissions and patients per nurse were significantly related to the likelihood of an AE (P < 0.05); occupancy rate, discharges, and DRG-weighted census were significant at P < 0.10. For example, a 0.1% increase in the patient-to-nurse ratio led to a 28% increase in the AE rate. Results at the other 3 hospitals varied and were mainly non significant. CONCLUSIONS: Hospitals that operate at or over capacity may experience heightened rates of patient safety events and might consider re-engineering the structures of care to respond better during periods of high stress. FAU - Weissman, Joel S AU - Weissman JS AD - Institute for Health Policy, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. jweissman@partners.org FAU - Rothschild, Jeffrey M AU - Rothschild JM FAU - Bendavid, Eran AU - Bendavid E FAU - Sprivulis, Peter AU - Sprivulis P FAU - Cook, E Francis AU - Cook EF FAU - Evans, R Scott AU - Evans RS FAU - Kaganova, Yevgenia AU - Kaganova Y FAU - Bender, Melissa AU - Bender M FAU - David-Kasdan, JoAnn AU - David-Kasdan J FAU - Haug, Peter AU - Haug P FAU - Lloyd, Jim AU - Lloyd J FAU - Selbovitz, Leslie G AU - Selbovitz LG FAU - Murff, Harvey J AU - Murff HJ FAU - Bates, David W AU - Bates DW LA - eng GR - 1 R01 HS12035/HS/AHRQ HHS/United States GR - R01 HS12035-02-S1/HS/AHRQ HHS/United States PT - Journal Article PT - Research Support, U.S. Gov't, P.H.S. PL - United States TA - Med Care JT - Medical care JID - 0230027 SB - IM MH - Aged MH - Bed Occupancy/statistics & numerical data MH - Diagnosis-Related Groups MH - Female MH - Hospitals, Teaching/*standards/statistics & numerical data MH - Humans MH - Male MH - Medical Audit MH - Medical Errors/statistics & numerical data/*trends MH - Middle Aged MH - Personnel, Hospital/psychology/*statistics & numerical data MH - Poisson Distribution MH - Quality of Health Care MH - Safety Management MH - United States MH - Workload/*statistics & numerical data EDAT- 2007/04/21 09:00 MHDA- 2007/06/15 09:00 CRDT- 2007/04/21 09:00 PHST- 2007/04/21 09:00 [pubmed] PHST- 2007/06/15 09:00 [medline] PHST- 2007/04/21 09:00 [entrez] AID - 00005650-200705000-00011 [pii] AID - 10.1097/01.mlr.0000257231.86368.09 [doi] PST - ppublish SO - Med Care. 2007 May;45(5):448-55. doi: 10.1097/01.mlr.0000257231.86368.09.