PMID- 17447508 OWN - NLM STAT- MEDLINE DCOM- 20070817 LR - 20181113 IS - 1863-6705 (Print) IS - 1863-6705 (Linking) VI - 55 IP - 3 DP - 2007 Mar TI - Tetralogy of Fallot in teenagers and adults: surgical experience and follow-up. PG - 105-12 AB - OBJECTIVE: The aim of this study was to review short- and long-term outcomes following total correction in patients with tetralogy of Fallot that presented during adulthood. METHODS: It was a retrospective analysis of 284 patients (aged 14-50 years, mean 19.4 +/- 2.5 years) with tetralogy of Fallot who underwent total correction at our institution between January 1991 and December 2001. Thirty patients were subjected to postoperative first-pass radionuclide angiocardiography scans. A Hindi version of the standard World Health Organization quality of life proforma was mailed to 120 patients operated on during the first half of the study period. RESULTS: Altogether, 45 (15.8%) patients had palliative shunts, and 32 (11%) had preoperative coil embolization. The transatrial/transpulmonary artery approach was used in 62 (22%) patients, the transventricular approach in 86 (30%) patients, and a combined approach in 136 (48%) patients. A transannular pericardial patch was used in 200 (70%) patients. A total of 61 (21%) patients had nonfatal complications. There were 28 hospital deaths. Follow-up ranged from 1 month to 10 years (mean 4.6 +/- 2.3 years). There were 7 (2.5%) late deaths and 6 (2.1%) reoperations. Altogether, 94% of patients were in New Yk Heart Association (NYHA) class I. Radionuclide angiocardiography showed normal right ventricular and left ventricular function in 18 (60%) and 22 (73%) patients, respectively. All of the 66 respondents perceived an improved quality of life. The actuarial survival and freedom from reoperation at 10 years were 82.88% +/- 3.80% and 92.82% +/- 3.40%, respectively. CONCLUSION: Total correction in this subset of patients offers the best option for long-term symptom-free survival. FAU - Bisoi, Akshay Kumar AU - Bisoi AK AD - Department of Cardiothoracic and Vascular Surgery, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India. bisoiak@rediffmail.com FAU - Murala, John Santosh Kumar AU - Murala JS FAU - Airan, Balram AU - Airan B FAU - Chowdhury, Ujjwal Kumar AU - Chowdhury UK FAU - Kothari, Shyam Sunder AU - Kothari SS FAU - Pal, Hemraj AU - Pal H FAU - Patel, Chetan D AU - Patel CD FAU - Sai Krishna, Cheemalapati AU - Sai Krishna C FAU - Chauhan, Sandeep AU - Chauhan S FAU - Panangipalli, Venugopal AU - Panangipalli V LA - eng PT - Journal Article PL - Japan TA - Gen Thorac Cardiovasc Surg JT - General thoracic and cardiovascular surgery JID - 101303952 SB - IM EIN - Gen Thorac Cardiovasc Surg. 2008 Apr;56(4):203. Cheemalapati, Sai Krishna [corrected to Sai Krishna, Cheemalapati] MH - Adolescent MH - Adult MH - Analysis of Variance MH - *Cardiac Surgical Procedures MH - Disease-Free Survival MH - Female MH - Follow-Up Studies MH - Humans MH - India MH - Male MH - Middle Aged MH - Quality of Life MH - Radionuclide Imaging MH - Reoperation MH - Research Design MH - Retrospective Studies MH - Risk Factors MH - Stroke Volume MH - Tetralogy of Fallot/diagnostic imaging/epidemiology/physiopathology/*surgery MH - Time Factors MH - Treatment Outcome EDAT- 2007/04/24 09:00 MHDA- 2007/08/19 09:00 CRDT- 2007/04/24 09:00 PHST- 2007/04/24 09:00 [pubmed] PHST- 2007/08/19 09:00 [medline] PHST- 2007/04/24 09:00 [entrez] AID - 10.1007/s11748-006-0087-1 [doi] PST - ppublish SO - Gen Thorac Cardiovasc Surg. 2007 Mar;55(3):105-12. doi: 10.1007/s11748-006-0087-1.