PMID- 17461113
OWN - NLM
STAT- MEDLINE
DCOM- 20070620
LR  - 20191110
IS  - 1615-9306 (Print)
IS  - 1615-9306 (Linking)
VI  - 30
IP  - 5
DP  - 2007 Mar
TI  - Assessment of the matrix effect on the headspace solid-phase microextraction 
      (HS-SPME) analysis of chlorophenols in wines.
PG  - 722-30
AB  - In this paper, we propose a comparative study to check the matrix effect on the 
      extraction of three chlorophenols, 2,4,6-trichlorophenol (TCP), 
      2,3,4,6-tetrachlorophenol and pentachlorophenol, direct precursors of 
      2,4,6-trichloroanisole, in synthetic and commercial wines (white and red wines). 
      A rapid, simple and sensitive methodology based on solid-phase microextraction 
      (SPME) and GC with electron capture detection (GC-ECD) and mass spectrometric 
      detection (GC-MS) was developed and the variables affecting the extraction 
      process (temperature, time and salt content) were examined employing a factorial 
      design at two levels. Since GC-ECD does not allow the clear identification of 
      target analytes in white wine, owing to overlapped interferences, GC-MS/MS was 
      used for subsequent examinations. Calibration curves were constructed in 
      synthetic, white and red wine. Significant differences between the slopes of 
      synthetic and red wine, with the exception of TCP, were observed. Analytical 
      parameters were evaluated and satisfactory results were obtained, showing the 
      usefulness of the headspace SPME (HS-SPME) method for determining chlorophenolic 
      compounds in wines.
FAU - Insa, Sara
AU  - Insa S
AD  - Department of Chemistry, University of Girona, Girona, Spain.
FAU - Besalu, Emili
AU  - Besalu E
FAU - Salvado, Victoria
AU  - Salvado V
FAU - Antico, Enriqueta
AU  - Antico E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - J Sep Sci
JT  - Journal of separation science
JID - 101088554
RN  - 0 (Chlorophenols)
RN  - 0 (Salts)
RN  - 0 (Solutions)
SB  - IM
MH  - Chlorophenols/*analysis/chemistry
MH  - Gas Chromatography-Mass Spectrometry
MH  - Salts
MH  - Solid Phase Microextraction/*methods
MH  - Solutions
MH  - Tandem Mass Spectrometry
MH  - Temperature
MH  - Wine/*analysis
EDAT- 2007/04/28 09:00
MHDA- 2007/06/21 09:00
CRDT- 2007/04/28 09:00
PHST- 2007/04/28 09:00 [pubmed]
PHST- 2007/06/21 09:00 [medline]
PHST- 2007/04/28 09:00 [entrez]
AID - 10.1002/jssc.200600021 [doi]
PST - ppublish
SO  - J Sep Sci. 2007 Mar;30(5):722-30. doi: 10.1002/jssc.200600021.