PMID- 17471472
OWN - NLM
STAT- MEDLINE
DCOM- 20080125
LR  - 20161124
IS  - 1522-7235 (Print)
IS  - 1522-7235 (Linking)
VI  - 22
IP  - 4
DP  - 2007 Jul-Aug
TI  - A new sensitive flow-injection chemiluminescence method for the determination of 
      H(2)-receptor antagonists.
PG  - 343-8
AB  - Based on the chemiluminescence (CL) intensity generated from the potassium 
      ferricyanide [K(3)Fe(CN)(6)]-rhodamine 6G system in sodium hydroxide (NaOH) 
      medium, a new sensitive flow-injection chemiluminescence (FI-CL) method has been 
      developed, validated and applied for the determination of three kinds of 
      H(2)-receptor antagonists: cimetidine (CIMT), ranitidine (RANT) hydrochloride and 
      famotidine (FAMT). Under the optimum conditions, the linear range for the 
      determination was 1.0 x 10(-9)-7.0 x 10(-5) g/ml for CIMT, 1.0 x 10(-9)-5.0 x 
      10(-5) g/mL for RANT hydrochloride and 5.0 x 10(-9)-7.0 x 10(-5) g/mL for FAMT. 
      During 11 repeated measurements of 1.0 x 10(-6) g/mL sample solutions, the 
      relative standard deviations (RSDs) were all <5%. The detection limit was 8.56 x 
      10(-10) g/mL for CIMT, 8.69 x 10(-10) g/mL for RANT hydrochloride and 2.35 x 
      10(-9) g/mL for FAMT (S:N = 3). This method has been successfully implemented for 
      the analysis of H(2)-receptor antagonists in pharmaceuticals.
CI  - (c) 2007 John Wiley & Sons, Ltd.
FAU - Tang, Yu-Hai
AU  - Tang YH
AD  - Institute of Analytical Chemistry, Xi'an Jiaotong University, Xi'an 710061, 
      People's Republic of China. tyh57@mail.xjtu.edu.cn
FAU - Wang, Nan-Nan
AU  - Wang NN
FAU - Xiong, Xun-Yu
AU  - Xiong XY
FAU - Xiong, Feng-Mei
AU  - Xiong FM
FAU - Sun, Si-Juan
AU  - Sun SJ
LA  - eng
PT  - Journal Article
PL  - England
TA  - Luminescence
JT  - Luminescence : the journal of biological and chemical luminescence
JID - 100889025
RN  - 0 (Ferricyanides)
RN  - 0 (Histamine H2 Antagonists)
RN  - 0 (Rhodamines)
RN  - 037VRW83CF (rhodamine 6G)
RN  - 5QZO15J2Z8 (Famotidine)
RN  - 80061L1WGD (Cimetidine)
RN  - 884KT10YB7 (Ranitidine)
RN  - U4MAF9C813 (potassium ferricyanide)
SB  - IM
MH  - Cimetidine/analysis
MH  - Famotidine/analysis
MH  - Ferricyanides
MH  - Flow Injection Analysis
MH  - Histamine H2 Antagonists/*analysis
MH  - Luminescent Measurements/*methods/standards
MH  - Ranitidine/analysis
MH  - Rhodamines
EDAT- 2007/05/02 09:00
MHDA- 2008/01/26 09:00
CRDT- 2007/05/02 09:00
PHST- 2007/05/02 09:00 [pubmed]
PHST- 2008/01/26 09:00 [medline]
PHST- 2007/05/02 09:00 [entrez]
AID - 10.1002/bio.969 [doi]
PST - ppublish
SO  - Luminescence. 2007 Jul-Aug;22(4):343-8. doi: 10.1002/bio.969.