PMID- 17476386
OWN - NLM
STAT- MEDLINE
DCOM- 20070815
LR  - 20131121
IS  - 1473-0197 (Print)
IS  - 1473-0189 (Linking)
VI  - 7
IP  - 5
DP  - 2007 May
TI  - Rapid fabrication of microchannels using microscale plasma activated templating 
      (microPLAT) generated water molds.
PG  - 641-3
AB  - Poly(dimethylsiloxane) (PDMS) is a common material used in fabricating 
      microfluidic devices. The predominant PDMS fabrication method, soft lithography, 
      relies on photolithography for fabrication of micropatterned molds. In this 
      technical note, we report an alternative molding technique using microscale 
      PLasma Activated Templating (microPLAT). The use of photoresist in soft 
      lithography is replaced by patterned water droplets created using microPLAT. When 
      liquid PDMS encapsulates patterned water and then solidifies, the cavities 
      occupied by water become structures such as microchannels. Using this method, 
      device fabrication is less time consuming, more cost efficient and flexible, and 
      ideal for rapid prototyping. An additional important feature of the water-molding 
      process is that it yields structural profiles that are difficult to achieve using 
      photolithography.
FAU - Chao, Shih-hui
AU  - Chao SH
AD  - Microscale Life Sciences Center, University of Washington, Seattle, USA. 
      joechao@u.washington.edu
FAU - Carlson, Robert
AU  - Carlson R
FAU - Meldrum, Deirdre R
AU  - Meldrum DR
LA  - eng
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20070405
PL  - England
TA  - Lab Chip
JT  - Lab on a chip
JID - 101128948
RN  - 059QF0KO0R (Water)
SB  - IM
MH  - Microfluidic Analytical Techniques/*instrumentation/*methods
MH  - Time Factors
MH  - *Water
EDAT- 2007/05/04 09:00
MHDA- 2007/08/19 09:00
CRDT- 2007/05/04 09:00
PHST- 2007/05/04 09:00 [pubmed]
PHST- 2007/08/19 09:00 [medline]
PHST- 2007/05/04 09:00 [entrez]
AID - 10.1039/b618269k [doi]
PST - ppublish
SO  - Lab Chip. 2007 May;7(5):641-3. doi: 10.1039/b618269k. Epub 2007 Apr 5.