PMID- 17482910
OWN - NLM
STAT- MEDLINE
DCOM- 20070703
LR  - 20070507
IS  - 1527-9995 (Electronic)
IS  - 0090-4295 (Linking)
VI  - 69
IP  - 5
DP  - 2007 May
TI  - Urinary symptoms associated with human T-cell lymphotropic virus type I 
      infection: evidence of urinary manifestations in large group of HTLV-I carriers.
PG  - 813-8
AB  - OBJECTIVES: To describe the frequency of urologic manifestations in human T-cell 
      lymphotropic virus type I (HTLV-I) seropositive individuals from Salvador and 
      other cities in Bahia, Brazil, with or without clinical HTLV-I-associated 
      myelopathy/tropical spastic paraparesis (HAM/TSP). METHODS: A total of 218 HTLV-I 
      seropositive subjects referred from blood banks or neurologic clinics were 
      admitted to the HTLV-I multidisciplinary outpatient clinic from January 2001 to 
      April 2004. They were assessed using a standardized questionnaire to determine 
      urinary complaints and quality of life. Neurologic impairment was established 
      using the Expanded Disability Status Scale (EDSS). HAM/TSP was considered as an 
      EDSS score of 2 or greater. RESULTS: Nocturia (35.8%) was the most frequent 
      finding, followed by incontinence (29.8%), urgency (25.2%), frequency (22.0%), 
      and dysuria (15.6%). Differences were found between individuals with an EDSS 
      score of 0 and those with an EDSS score greater than 0 but less than 2 regarding 
      frequency, nocturia, urgency, urinary loss of any degree, and quality of life. 
      Dysuria and great or total urinary loss were more frequent among those with 
      severe HAM/TSP (EDSS score greater than 6). CONCLUSIONS: Even HTLV-I subjects 
      considered not to have HAM/TSP may have prominent urinary findings already 
      present. Urologic manifestations, including nocturia and urinary loss, might be 
      early manifestations of neurologic disease in those with HTLV-I.
FAU - Castro, Neviton M
AU  - Castro NM
AD  - Servico de Imunologia do Hospital Unversitario Prof. Edgard Santos, Universidade 
      Federal da Bahia, Salvador, Bahia, Brazil. neviton_castro@uol.com.br
FAU - Rodrigues, Waldyr Jr
AU  - Rodrigues W Jr
FAU - Freitas, Daniel M
AU  - Freitas DM
FAU - Muniz, Andre
AU  - Muniz A
FAU - Oliveira, Paulo
AU  - Oliveira P
FAU - Carvalho, Edgar M
AU  - Carvalho EM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Urology
JT  - Urology
JID - 0366151
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Distribution
MH  - Aged
MH  - Aged, 80 and over
MH  - Blotting, Western
MH  - Brazil/epidemiology
MH  - Carrier State/diagnosis/*epidemiology/*virology
MH  - Cohort Studies
MH  - Comorbidity
MH  - Dysuria/epidemiology/virology
MH  - Female
MH  - HTLV-I Infections/diagnosis/*epidemiology
MH  - Human T-lymphotropic virus 1/*isolation & purification
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Nocturia/epidemiology/virology
MH  - Odds Ratio
MH  - Probability
MH  - Prognosis
MH  - Retrospective Studies
MH  - Serologic Tests
MH  - Severity of Illness Index
MH  - Sex Distribution
MH  - Urination Disorders/diagnosis/*epidemiology
EDAT- 2007/05/08 09:00
MHDA- 2007/07/04 09:00
CRDT- 2007/05/08 09:00
PHST- 2005/04/08 00:00 [received]
PHST- 2006/11/05 00:00 [revised]
PHST- 2007/01/21 00:00 [accepted]
PHST- 2007/05/08 09:00 [pubmed]
PHST- 2007/07/04 09:00 [medline]
PHST- 2007/05/08 09:00 [entrez]
AID - S0090-4295(07)00116-1 [pii]
AID - 10.1016/j.urology.2007.01.052 [doi]
PST - ppublish
SO  - Urology. 2007 May;69(5):813-8. doi: 10.1016/j.urology.2007.01.052.