PMID- 17485941
OWN - NLM
STAT- MEDLINE
DCOM- 20070621
LR  - 20190606
IS  - 0916-7250 (Print)
IS  - 0916-7250 (Linking)
VI  - 69
IP  - 4
DP  - 2007 Apr
TI  - A case of hyperplastic dermatosis of the West Highland White Terrier controlled 
      by recombinant canine interferon-gamma therapy.
PG  - 455-7
AB  - A 3.5-year-old, male West Highland White Terrier was diagnosed as having 
      hyperplastic dermatosis by clinical and histopathological findings. Controlling 
      of Malassezia overgrowth by antifungal drugs provided a temporal improvement of 
      the skin lesions, but the disease was deteriorated within the next 2 months 
      despite the negative demonstration of the yeasts. Induction of recombinant canine 
      interferon-gamma (rCaIFN-gamma) therapy resulted in almost complete cure of the 
      skin lesions within 2 months after the initiation of the therapy. No adverse 
      effects were detected during the therapy. Our results suggested that the 
      rCaIFN-gamma therapy is potential to be a novel therapeutic option for 
      controlling the breed-specific hyperplastic skin disease.
FAU - Nishifuji, Koji
AU  - Nishifuji K
AD  - Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.
FAU - Park, Seong-Jun
AU  - Park SJ
FAU - Iwasaki, Toshiroh
AU  - Iwasaki T
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Japan
TA  - J Vet Med Sci
JT  - The Journal of veterinary medical science
JID - 9105360
RN  - 82115-62-6 (Interferon-gamma)
SB  - IM
MH  - Animals
MH  - Dog Diseases/*drug therapy/pathology
MH  - Dogs
MH  - Hyperplasia
MH  - Interferon-gamma/*therapeutic use
MH  - Male
MH  - Skin Diseases/*drug therapy/pathology/*veterinary
EDAT- 2007/05/09 09:00
MHDA- 2007/06/22 09:00
CRDT- 2007/05/09 09:00
PHST- 2007/05/09 09:00 [pubmed]
PHST- 2007/06/22 09:00 [medline]
PHST- 2007/05/09 09:00 [entrez]
AID - JST.JSTAGE/jvms/69.455 [pii]
AID - 10.1292/jvms.69.455 [doi]
PST - ppublish
SO  - J Vet Med Sci. 2007 Apr;69(4):455-7. doi: 10.1292/jvms.69.455.