PMID- 17486566
OWN - NLM
STAT- MEDLINE
DCOM- 20070918
LR  - 20071115
IS  - 0091-2751 (Print)
IS  - 0091-2751 (Linking)
VI  - 35
IP  - 6
DP  - 2007 Jul-Aug
TI  - Value of ultrasound-guided core biopsy in the diagnosis of malignant lymphoma.
PG  - 295-301
AB  - PURPOSE: Ultrasound-guided core needle biopsy for the diagnosis and management of 
      malignant lymphomas is controversial and has not been accepted as an alternative 
      to surgical biopsy. We investigate the clinical usefulness of this procedure in a 
      large series of patients. METHODS: Over a 5-year period (2000-2004), 
      ultrasound-guided core needle biopsies were performed in 102 malignant lymphomas. 
      Five diagnostic categories were considered: large B-cell lymphomas (LBCL), small 
      B-cell lymphomas (SBCL), Hodgkin's disease (HD), T cell lymphomas, and 
      miscellaneous. Surgical excisional biopsy of the node was performed in 47 cases 
      (46.1%) for diagnostic confirmation. RESULTS: The overall diagnostic accuracy of 
      ultrasound-guided core needle biopsy was 88.2% (90/102). SBCL (39), LBCL (36), HD 
      (15), T cell lymphomas (5), and miscellaneous (7) [including T cell-rich B cell 
      (2), natural killer cell (1), Burkitt's lymphoma (1), and non-Hodgkin's lymphoma 
      of the B cell type, NOS (3)] were correctly diagnosed. Three HDs, 1 natural 
      killer cell lymphoma, 1 follicular lymphoma, and 1 LBCL were not correctly 
      diagnosed. The core needle biopsy did not yield tumor tissue in 6 cases. 
      CONCLUSIONS: Ultrasound-guided core needle biopsy is effective in the diagnosis 
      of malignant lymphomas and can be used as the first diagnostic approach in 
      selected clinical situations.
CI  - (c) 2007 Wiley Periodicals, Inc.
FAU - de Larrinoa, Aitor Fernandez
AU  - de Larrinoa AF
AD  - Department of Anatomic Pathology, Hospital de Basurto, Avda. de Montevideo 18, 
      Bilbao, 48013 Spain.
FAU - del Cura, Jose
AU  - del Cura J
FAU - Zabala, Rosa
AU  - Zabala R
FAU - Fuertes, Elena
AU  - Fuertes E
FAU - Bilbao, Francisco
AU  - Bilbao F
FAU - Lopez, Jose I
AU  - Lopez JI
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Clin Ultrasound
JT  - Journal of clinical ultrasound : JCU
JID - 0401663
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Biopsy/*methods
MH  - Burkitt Lymphoma/diagnosis/pathology
MH  - Female
MH  - Hodgkin Disease/diagnosis
MH  - Humans
MH  - Killer Cells, Natural/pathology
MH  - Leukemia, Lymphocytic, Chronic, B-Cell/diagnosis
MH  - Lymph Nodes/pathology
MH  - Lymphoma/*diagnosis/pathology
MH  - Lymphoma, B-Cell/diagnosis
MH  - Lymphoma, Follicular/diagnosis
MH  - Lymphoma, Large B-Cell, Diffuse/diagnosis
MH  - Lymphoma, T-Cell/diagnosis
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - *Ultrasonography, Interventional
EDAT- 2007/05/09 09:00
MHDA- 2007/09/19 09:00
CRDT- 2007/05/09 09:00
PHST- 2007/05/09 09:00 [pubmed]
PHST- 2007/09/19 09:00 [medline]
PHST- 2007/05/09 09:00 [entrez]
AID - 10.1002/jcu.20383 [doi]
PST - ppublish
SO  - J Clin Ultrasound. 2007 Jul-Aug;35(6):295-301. doi: 10.1002/jcu.20383.