PMID- 17500731
OWN - NLM
STAT- MEDLINE
DCOM- 20070703
LR  - 20071203
IS  - 1539-3755 (Print)
IS  - 1539-3755 (Linking)
VI  - 75
IP  - 3 Pt 1
DP  - 2007 Mar
TI  - Spike patterning of a stochastic phase model neuron given periodic inhibition.
PG  - 031912
AB  - We present a phase model of a repetitively firing neuron possessing a 
      phase-dependent stochastic response to periodic inhibition. We analyze the 
      dynamics in terms of a stochastic phase map and determine the invariant phase 
      distribution. We use the latter to compute both the distribution of interspike 
      intervals (ISIs) and the stochastic winding number (mean firing rate) as a 
      function of the input frequency. We show that only low-order phase locking 
      persists in the presence of weak phase dependence, and is characterized 
      statistically by a multimodal ISI distribution and a nonmonotonic variation in 
      the stochastic winding number as a function of input frequency.
FAU - Nesse, William H
AU  - Nesse WH
AD  - Department of Mathematics, University of Utah, Salt Lake City, Utah 84112, USA.
FAU - Clark, Gregory A
AU  - Clark GA
FAU - Bressloff, Paul C
AU  - Bressloff PC
LA  - eng
GR  - R01-MH068392/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20070326
PL  - United States
TA  - Phys Rev E Stat Nonlin Soft Matter Phys
JT  - Physical review. E, Statistical, nonlinear, and soft matter physics
JID - 101136452
SB  - IM
MH  - Action Potentials/*physiology
MH  - Biological Clocks/*physiology
MH  - Computer Simulation
MH  - Feedback/physiology
MH  - *Models, Neurological
MH  - Nerve Net/physiology
MH  - Neural Inhibition/*physiology
MH  - *Periodicity
MH  - Stochastic Processes
MH  - Synaptic Transmission/*physiology
EDAT- 2007/05/16 09:00
MHDA- 2007/07/04 09:00
CRDT- 2007/05/16 09:00
PHST- 2006/11/27 00:00 [received]
PHST- 2007/05/16 09:00 [pubmed]
PHST- 2007/07/04 09:00 [medline]
PHST- 2007/05/16 09:00 [entrez]
AID - 10.1103/PhysRevE.75.031912 [doi]
PST - ppublish
SO  - Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Mar;75(3 Pt 1):031912. doi: 
      10.1103/PhysRevE.75.031912. Epub 2007 Mar 26.