PMID- 17503515
OWN - NLM
STAT- MEDLINE
DCOM- 20070821
LR  - 20191210
IS  - 1522-1946 (Print)
IS  - 1522-1946 (Linking)
VI  - 70
IP  - 1
DP  - 2007 Jul 1
TI  - Feasibility of transcatheter intervention for severe aortic stenosis in patients 
      >or=90 years of age: aortic valvuloplasty revisited.
PG  - 149-54
AB  - OBJECTIVES: The goals of this study were to determine the feasibility, safety, 
      and early outcomes of balloon aortic valvuloplasty (BAV) for severe aortic 
      stenosis in a nonagenarian population. BACKGROUND: This very elderly population 
      is expanding rapidly, has a high incidence of aortic stenosis, and uncommonly 
      undergoes surgical aortic valve replacement. These patients may best be treated 
      with a transcatheter approach due to comorbidities, surgical risk, and personal 
      preference. METHODS: We reviewed 31 consecutive patients >or=90 years of age who 
      underwent BAV at our institution from July 2003 to August 2006 for data pertinent 
      to patient characteristics, procedural techniques, and 30-day outcomes. RESULTS: 
      Our patients had a mean age of 93 +/- 3.0 years (90-101). The society of thoracic 
      surgery risk score was 18.5 (+/-10.2) and logistic Euroscore was 35.8 (+/-19.3). 
      Twenty-five patients (81%) underwent retrograde BAV and 6 (19%) antegrade BAV. 
      Five patients (16%) underwent combined BAV and coronary stenting. Overall mean 
      aortic valve area increased from 0.52 cm2 (+/-0.17) to 0.92 cm2 (+/-0.22) and 
      mean New York Heart Association (NYHA) functional class improved from 3.4 to 1.8. 
      Intraprocedural mortality occurred in one patient (3.2%) and 30-day mortality in 
      three patients (9.7%). CONCLUSIONS: BAV can be carried out in high risk 
      nonagenarian patients with an acceptable complication rate, low perioperative 
      mortality, and early improvement in NYHA functional class.
CI  - (c) 2007 Wiley-Liss, Inc.
FAU - Pedersen, Wes R
AU  - Pedersen WR
AD  - Minneapolis Heart Institute Foundation at Abbott Northwestern Hospital, 
      Minneapolis, Minnesota 55407, USA. Wesley.Pedersen@allina.com
FAU - Klaassen, Paul J
AU  - Klaassen PJ
FAU - Boisjolie, Charlene R
AU  - Boisjolie CR
FAU - Pierce, Talia A
AU  - Pierce TA
FAU - Harris, Kevin M
AU  - Harris KM
FAU - Lesser, John R
AU  - Lesser JR
FAU - Hara, Hidehiko
AU  - Hara H
FAU - Mooney, Michael R
AU  - Mooney MR
FAU - Graham, Kevin J
AU  - Graham KJ
FAU - Kshettry, Vibhu R
AU  - Kshettry VR
FAU - Goldenberg, Irvin F
AU  - Goldenberg IF
FAU - Priztker, Marc R
AU  - Priztker MR
FAU - Van Tassel, Robert A
AU  - Van Tassel RA
FAU - Schwartz, Robert S
AU  - Schwartz RS
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PL  - United States
TA  - Catheter Cardiovasc Interv
JT  - Catheterization and cardiovascular interventions : official journal of the 
      Society for Cardiac Angiography & Interventions
JID - 100884139
SB  - IM
CIN - Catheter Cardiovasc Interv. 2007 Jul 1;70(1):155. PMID: 17585393
MH  - Age Factors
MH  - Aged, 80 and over
MH  - Aortic Valve Stenosis/mortality/pathology/physiopathology/*therapy
MH  - *Catheterization/adverse effects/mortality
MH  - Feasibility Studies
MH  - Female
MH  - Humans
MH  - Male
MH  - *Patient Selection
MH  - Research Design
MH  - Risk Assessment
MH  - Severity of Illness Index
MH  - *Stents
MH  - Time Factors
MH  - Treatment Outcome
EDAT- 2007/05/16 09:00
MHDA- 2007/08/22 09:00
CRDT- 2007/05/16 09:00
PHST- 2007/05/16 09:00 [pubmed]
PHST- 2007/08/22 09:00 [medline]
PHST- 2007/05/16 09:00 [entrez]
AID - 10.1002/ccd.21161 [doi]
PST - ppublish
SO  - Catheter Cardiovasc Interv. 2007 Jul 1;70(1):149-54. doi: 10.1002/ccd.21161.