PMID- 17510505
OWN - NLM
STAT- MEDLINE
DCOM- 20070725
LR  - 20151119
IS  - 0916-9636 (Print)
IS  - 0916-9636 (Linking)
VI  - 30
IP  - 3
DP  - 2007 Mar
TI  - Pulse wave velocity as a marker of arteriosclerosis and its comorbidities in 
      Chinese patients.
PG  - 237-42
AB  - To obtain reliable data on the epidemiology of arteriosclerosis and the 
      comorbidities in patients with hypertension (HP), coronary heart disease (CHD), 
      type 2 diabetes mellitus (T2DM) and stroke, we evaluated the clinical 
      significance of pulse wave velocity (PWV) as an indicator of arteriosclerosis and 
      its comorbidities in Chinese patients. A total of 910 subjects, including 748 
      Chinese patients with one or more cardiovascular risk factors (80.2% male, mean 
      age 73.69+/-5.03 years) and 162 healthy volunteers (78.4% male, mean age 
      73.60+/-5.32 years) were recruited into the study. PWV was measured in 910 
      subjects, and large artery arteriosclerosis was defined as PWV >or=12 m/s. 
      Multivariable logistic regression analyses were performed to identify risk 
      factors associated with arteriosclerosis. The prevalence of large artery 
      arteriosclerosis in the patients overall was 67.4%, and the prevalence was higher 
      in patients with than in those without HP (63.3% vs. 34.0%; odds ratio [OR]: 
      3.451), T2DM (24.8% vs. 11.1%; OR: 2.854), CHD (56.1% vs. 45.1%; OR: 1.246) and 
      stroke (26.6% vs. 19.2%; OR: 1.236), but the OR values of CHD and stroke did not 
      differ significantly (p>0.05). After multiple logistic regression analysis, 
      female sex, older age, HP and T2DM were risk factors for large artery 
      arteriosclerosis. In conclusion, PWV can be used as a routine measurement to scan 
      arteriosclerosis in patients with HP or T2DM.
FAU - Liu, Xiao-Ning
AU  - Liu XN
AD  - Department of Geriatrics, Qi-Lu Hospital of Shandong University, Jinan, PR China.
FAU - Gao, Hai-Qing
AU  - Gao HQ
FAU - Li, Bao-Ying
AU  - Li BY
FAU - Cheng, Mei
AU  - Cheng M
FAU - Ma, Ya-Bing
AU  - Ma YB
FAU - Zhang, Zhi-Mian
AU  - Zhang ZM
FAU - Gao, Xi-Mei
AU  - Gao XM
FAU - Liu, Yuan-Ping
AU  - Liu YP
FAU - Wang, Min
AU  - Wang M
LA  - eng
PT  - Journal Article
PL  - England
TA  - Hypertens Res
JT  - Hypertension research : official journal of the Japanese Society of Hypertension
JID - 9307690
RN  - 0 (Biomarkers)
SB  - IM
MH  - Aged
MH  - Arteriosclerosis/diagnosis/epidemiology/*physiopathology
MH  - Biomarkers
MH  - Blood Pressure/*physiology
MH  - Carotid Arteries/physiology
MH  - China/epidemiology
MH  - Comorbidity
MH  - Coronary Disease/diagnosis/epidemiology/*physiopathology
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/diagnosis/epidemiology/*physiopathology
MH  - Female
MH  - Femoral Artery/physiology
MH  - Humans
MH  - Hypertension/diagnosis/epidemiology/physiopathology
MH  - Male
MH  - Regional Blood Flow/physiology
MH  - Risk Factors
MH  - Stroke/diagnosis/epidemiology/*physiopathology
EDAT- 2007/05/19 09:00
MHDA- 2007/07/26 09:00
CRDT- 2007/05/19 09:00
PHST- 2007/05/19 09:00 [pubmed]
PHST- 2007/07/26 09:00 [medline]
PHST- 2007/05/19 09:00 [entrez]
AID - JST.JSTAGE/hypres/30.237 [pii]
AID - 10.1291/hypres.30.237 [doi]
PST - ppublish
SO  - Hypertens Res. 2007 Mar;30(3):237-42. doi: 10.1291/hypres.30.237.