PMID- 17517180
OWN - NLM
STAT- MEDLINE
DCOM- 20070712
LR  - 20070522
IS  - 0366-6999 (Print)
IS  - 0366-6999 (Linking)
VI  - 120
IP  - 8
DP  - 2007 Apr 20
TI  - Mid-term effects of lung volume reduction surgery on pulmonary function in 
      patients with chronic obstructive pulmonary disease.
PG  - 658-62
AB  - BACKGROUND: Now lung volume reduction surgery (LVRS) has become one of the most 
      effective methods for the management of some cases of severe chronic obstructive 
      pulmonary disease (COPD). We evaluated the mid-term effects of LVRS on pulmonary 
      function in patients with severe COPD. METHODS: Ten male patients with severe 
      COPD aged 38 - 70 years underwent LVRS and their pulmonary function was assessed 
      before, 3 months and 3 years after surgery. The spirometric and gas exchange 
      parameters included residual volume, total lung capacity, inspiratory capacity, 
      forced vital capacity, forced expiratory volume in one second, diffusion capacity 
      for CO, and arterial blood gas. A 6-minute walk distance (6MWD) test was 
      performed. RESULTS: As to preoperative assessment, most spirometric parameters 
      and 6MWD were significantly improved after 3 months and slightly 3 years after 
      LVRS. Gas exchange parameters were significantly improved 3 months after surgery, 
      but returned to the preoperative levels after 3 years. CONCLUSIONS: LVRS may 
      significantly improve pulmonary function in patients with severe COPD indicating 
      for LVRS. Mid-term pulmonary function 3 years after surgery can be decreased to 
      the level at 3 months after surgery. Three years after LVRS, lung volume and 
      pulmonary ventilation function can be significantly improved, but the improvement 
      in gas exchange function was not significant.
FAU - Liu, Jin-Ming
AU  - Liu JM
AD  - Department of Respiratory Medicine, Pulmonary Function Test Laboratory and 
      Department of Thoracic Surgery, Shanghai Pneumology Hospital, Tongji University, 
      Shanghai, China. Jinming_Liu@hotmail.com
FAU - Yang, Wen-Lan
AU  - Yang WL
FAU - Jiang, Ge-Ning
AU  - Jiang GN
FAU - Ding, Jia-An
AU  - Ding JA
FAU - Zheng, Wei
AU  - Zheng W
FAU - Liu, Wen-Zeng
AU  - Liu WZ
FAU - Wang, Ying-Min
AU  - Wang YM
FAU - Gao, Bei-Lan
AU  - Gao BL
FAU - Jiang, Ping
AU  - Jiang P
FAU - Wu, Wen
AU  - Wu W
FAU - Li, Xia
AU  - Li X
FAU - Bjorn, Jonson
AU  - Bjorn J
LA  - eng
PT  - Journal Article
PL  - China
TA  - Chin Med J (Engl)
JT  - Chinese medical journal
JID - 7513795
SB  - IM
MH  - Adult
MH  - Aged
MH  - Exercise Tolerance
MH  - Humans
MH  - Lung Volume Measurements
MH  - Male
MH  - Middle Aged
MH  - Pneumonectomy/adverse effects/*methods
MH  - Pulmonary Disease, Chronic Obstructive/pathology/*physiopathology/*surgery
MH  - Respiratory Function Tests
MH  - Time Factors
EDAT- 2007/05/23 09:00
MHDA- 2007/07/13 09:00
CRDT- 2007/05/23 09:00
PHST- 2007/05/23 09:00 [pubmed]
PHST- 2007/07/13 09:00 [medline]
PHST- 2007/05/23 09:00 [entrez]
PST - ppublish
SO  - Chin Med J (Engl). 2007 Apr 20;120(8):658-62.