PMID- 17523112
OWN - NLM
STAT- MEDLINE
DCOM- 20080623
LR  - 20130520
IS  - 1576-6578 (Electronic)
IS  - 0210-0010 (Linking)
VI  - 44 Suppl 3
DP  - 2007 May 21
TI  - [Genetic advances in attention deficit hyperactivity disorder].
PG  - S51-2
AB  - AIM: To update the knowledge currently available on the genetic foundations of 
      attention deficit hyperactivity disorder (ADHD). The presentation will focus 
      especially on recent data concerning adults. DEVELOPMENT AND CONCLUSIONS: ADHD is 
      one of the most prevalent neuropsychiatric disorders among the general childhood 
      population. In recent years it has been shown that it often progresses into 
      adulthood. The results from studies of families, twins and adopted children 
      display a high degree of familial aggregation. Molecular genetics studies have 
      brought to light positive associations with different genetic polymorphisms in 
      neurotransmitter systems involved in the pathophysiology of ADHD, mainly with the 
      dopaminergic, serotoninergic and noradrenergic, and neurotrophins such as the 
      brain-derived neurotrophic factor (BDNF). The causation of ADHD is still largely 
      unknown but the different studies published to date dealing with the genetic 
      foundations of the disorder suggest that genetics play an important role, its 
      inheritance is complex and it is modulated by environmental factors. ADHD in 
      adults can be a good model for studying the genetic foundations of ADHD.
FAU - Ramos-Quiroga, J A
AU  - Ramos-Quiroga JA
AD  - Universitat Autonoma de Barcelona. Facultat de Medicina. Unitat docent de 
      l'Hospital Vall d'Heb, 08035 Barcelona, Espana. jaramos@vhebron.net
FAU - Ribases-Haro, M
AU  - Ribases-Haro M
FAU - Bosch-Munso, R
AU  - Bosch-Munso R
FAU - Cormand-Rifa, B
AU  - Cormand-Rifa B
FAU - Casas, M
AU  - Casas M
LA  - spa
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - Avances geneticos en el trastorno por deficit de atencion/hiperactividad.
PL  - Spain
TA  - Rev Neurol
JT  - Revista de neurologia
JID - 7706841
SB  - IM
MH  - Adult
MH  - Attention Deficit Disorder with Hyperactivity/*genetics
MH  - Child
MH  - Humans
RF  - 14
EDAT- 2007/05/25 09:00
MHDA- 2008/06/24 09:00
CRDT- 2007/05/25 09:00
PHST- 2007/05/25 09:00 [pubmed]
PHST- 2008/06/24 09:00 [medline]
PHST- 2007/05/25 09:00 [entrez]
AID - rn2007231 [pii]
PST - ppublish
SO  - Rev Neurol. 2007 May 21;44 Suppl 3:S51-2.