PMID- 17523562
OWN - NLM
STAT- MEDLINE
DCOM- 20070619
LR  - 20191210
IS  - 0885-3010 (Print)
IS  - 0885-3010 (Linking)
VI  - 54
IP  - 5
DP  - 2007 May
TI  - Intravascular photoacoustic imaging using an IVUS imaging catheter.
PG  - 978-86
AB  - Catheter-based imaging of atherosclerosis with high resolution, albeit invasive, 
      is extremely important for screening and characterization of vulnerable plaques. 
      Currently, there is a need for an imaging technique capable of providing 
      comprehensive morphological and functional information of plaques. In this paper, 
      we present an intravascular photoacoustic imaging technique to characterize 
      vulnerable plaques by using optical absorption contrast between normal tissue and 
      atherosclerotic lesions. Specifically, we investigate the feasibility of 
      obtaining intravascular photoacoustic (IVPA) images using a high-frequency 
      intravascular ultrasound (IVUS) imaging catheter. Indeed, the combination of IVPA 
      imaging with clinically available IVUS imaging may provide desired functional and 
      morphological assessment of the plaque. The imaging studies were performed with 
      tissue-mimicking arterial vessel phantoms and excised samples of rabbit artery. 
      The results of our study suggest that catheter-based intravascular photoacoustic 
      imaging is possible, and the combination of IVPA with IVUS has the potential to 
      detect and differentiate atherosclerosis based on both the structure and 
      composition of the plaque.
FAU - Sethuraman, Shriram
AU  - Sethuraman S
AD  - Department of Biomedical Engineering, The University of Texas at Austin, Austin, 
      TX 78712, USA.
FAU - Aglyamov, Salavat R
AU  - Aglyamov SR
FAU - Amirian, James H
AU  - Amirian JH
FAU - Smalling, Richard W
AU  - Smalling RW
FAU - Emelianov, Stanislav Y
AU  - Emelianov SY
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - IEEE Trans Ultrason Ferroelectr Freq Control
JT  - IEEE transactions on ultrasonics, ferroelectrics, and frequency control
JID - 9882735
SB  - IM
MH  - Animals
MH  - Atherosclerosis/*diagnostic imaging
MH  - *Catheterization
MH  - Equipment Design
MH  - Equipment Failure Analysis
MH  - Image Enhancement/*instrumentation/methods
MH  - In Vitro Techniques
MH  - Microscopy, Acoustic/*instrumentation/methods
MH  - Phantoms, Imaging
MH  - Rabbits
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Ultrasonography, Interventional/*instrumentation/methods
EDAT- 2007/05/26 09:00
MHDA- 2007/06/20 09:00
CRDT- 2007/05/26 09:00
PHST- 2007/05/26 09:00 [pubmed]
PHST- 2007/06/20 09:00 [medline]
PHST- 2007/05/26 09:00 [entrez]
AID - 10.1109/tuffc.2007.343 [doi]
PST - ppublish
SO  - IEEE Trans Ultrason Ferroelectr Freq Control. 2007 May;54(5):978-86. doi: 
      10.1109/tuffc.2007.343.