PMID- 1752904 OWN - NLM STAT- MEDLINE DCOM- 19920130 LR - 20161026 IS - 0021-9509 (Print) IS - 0021-9509 (Linking) VI - 32 IP - 6 DP - 1991 Nov-Dec TI - Clinical results with the Biocor porcine bioprosthesis. PG - 807-13 AB - In order to evaluate our clinical results with the use of the Biocor prosthesis, a total of 1,101 patients were studied. Follow-up was from 1 to 96 months (mean 48); cumulative follow-up in the aortic group (385 patients) was 1,230 patient years and in the mitral group (716 patients) 3,018 patient years. Mitral patients had 102 late complications (14.24%), and aortic patients had 51 (13.2%). A total of 220 patients were under 20 years of age (176 mitral, 44 aortic). Intrinsic valve failure in this subgroup was found in 43% of mitral patients and 29% of aortic patients. Prosthetic endocarditis was more frequent in the aortic group (45%) than in the mitral group (29.9%). Sixty-two patients were reoperated, with a hospital mortality of 12.6%. Reoperation was more frequent in the mitral group and in patients under 20 years of age. The actuarial curve free mortality related to the bioprosthesis was 97.1% (32 patients). At the 8-year follow-up, 96.9% of the aortic versus 95.2% of the mitral group were free of valve dysfunction, and the majority were in Classes I or II of the New York Heart Association (NYHA) classification. The incidence of reoperation, although significant, is acceptable, especially since the bioprosthesis offers a safer alternative than mechanical prostheses followed for similar periods. Analysis of our results suggests the need for continued research for an ideal bioprosthesis. FAU - Vrandecic, M O AU - Vrandecic MO AD - Santa Casa de Misericordia de Belo Horizonte, Brazil. FAU - Gontijo Filho, B AU - Gontijo Filho B FAU - Paula e Silva, J A AU - Paula e Silva JA FAU - Fantini, F A AU - Fantini FA FAU - Barbosa, J T AU - Barbosa JT FAU - Sao Jose, M C AU - Sao Jose MC FAU - Dos Santos Pinto, C A AU - Dos Santos Pinto CA FAU - Vieira, G L AU - Vieira GL FAU - Oliveira, H G AU - Oliveira HG FAU - Rabelo, S AU - Rabelo S AU - et al. LA - eng PT - Journal Article PL - Italy TA - J Cardiovasc Surg (Torino) JT - The Journal of cardiovascular surgery JID - 0066127 SB - IM MH - Actuarial Analysis MH - Adult MH - Aortic Valve MH - *Bioprosthesis MH - Child MH - Follow-Up Studies MH - Heart Valve Prosthesis/*mortality MH - Hospital Mortality MH - Humans MH - Incidence MH - Mitral Valve MH - Postoperative Complications/mortality MH - Prosthesis Design MH - Prosthesis-Related Infections/mortality MH - Reoperation MH - Time Factors EDAT- 1991/11/01 00:00 MHDA- 1991/11/01 00:01 CRDT- 1991/11/01 00:00 PHST- 1991/11/01 00:00 [pubmed] PHST- 1991/11/01 00:01 [medline] PHST- 1991/11/01 00:00 [entrez] PST - ppublish SO - J Cardiovasc Surg (Torino). 1991 Nov-Dec;32(6):807-13.