PMID- 17532498
OWN - NLM
STAT- MEDLINE
DCOM- 20070831
LR  - 20090827
IS  - 0967-5868 (Print)
IS  - 0967-5868 (Linking)
VI  - 14
IP  - 7
DP  - 2007 Jul
TI  - Pharmacoeconomics of therapy for Guillain-Barre syndrome: plasma exchange and 
      intravenous immunoglobulin.
PG  - 625-9
AB  - Guillain-Barre syndrome (GBS) is an acute neuropathy and a clinical syndrome that 
      includes a number of pathological and electrophysiological subtypes. Intravenous 
      immunoglobulin (IVIG) and plasma exchange (PE) are both equally efficacious for 
      the treatment of GBS; however, the cost of IVIG may be lower for both the patient 
      and the healthcare system. To compare the pharmacoeconomics of PE and IVIG in 
      GBS, a retrospective study was done from 1999 to 2004, which included a total of 
      24 patients with GBS who were admitted to Taipei Veterans General Hospital. This 
      showed that except for the costs of the drugs used in IVIG, treatment of GBS with 
      IVIG was more cost-effective (p=0.057) than that with PE in total length of 
      hospitalization and the cost of procedures and hospitalization. The study also 
      showed that the total costs were higher for patients on ventilators than those 
      not requiring ventilators (p=0.008, t-test) and the length of hospitalization 
      showed a very strong linear relationship to total costs (Pearson correlation 
      coefficient=0.907). The regression analysis showed that each additional day of 
      hospitalization increased the hospitalization costs by an average of 5599 New 
      Taiwan Dollars (NT) (US$1.00=NT$33.50 in 2005).
FAU - Tsai, Ching-Piao
AU  - Tsai CP
AD  - Neurology, The Neurological Institute, Taipei Veterans General Hospital and 
      Taipei City Hospital, 201, Sec. 2 Shih-Pai Road, Taipei 112, Taiwan. 
      cptsai@vghtpe.gov.tw
FAU - Wang, Kai-Chen
AU  - Wang KC
FAU - Liu, Chih-Yang
AU  - Liu CY
FAU - Sheng, Wen-Yung
AU  - Sheng WY
FAU - Lee, Tzu-Chi
AU  - Lee TC
LA  - eng
PT  - Journal Article
PL  - Scotland
TA  - J Clin Neurosci
JT  - Journal of clinical neuroscience : official journal of the Neurosurgical Society 
      of Australasia
JID - 9433352
RN  - 0 (Immunoglobulins, Intravenous)
SB  - IM
CIN - J Clin Neurosci. 2009 Aug;16(8):1110; author reply 1111. PMID: 19467870
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Analysis of Variance
MH  - Child
MH  - *Costs and Cost Analysis
MH  - Drug Costs
MH  - *Economics, Pharmaceutical
MH  - Female
MH  - Guillain-Barre Syndrome/drug therapy/*economics
MH  - Humans
MH  - Immunoglobulins, Intravenous/*economics/therapeutic use
MH  - Length of Stay
MH  - Linear Models
MH  - Male
MH  - Middle Aged
MH  - Plasma Exchange/*economics/methods
MH  - Retrospective Studies
EDAT- 2007/05/29 09:00
MHDA- 2007/09/01 09:00
CRDT- 2007/05/29 09:00
PHST- 2006/01/25 00:00 [received]
PHST- 2006/03/26 00:00 [revised]
PHST- 2006/03/29 00:00 [accepted]
PHST- 2007/05/29 09:00 [pubmed]
PHST- 2007/09/01 09:00 [medline]
PHST- 2007/05/29 09:00 [entrez]
AID - S0967-5868(06)00280-3 [pii]
AID - 10.1016/j.jocn.2006.03.020 [doi]
PST - ppublish
SO  - J Clin Neurosci. 2007 Jul;14(7):625-9. doi: 10.1016/j.jocn.2006.03.020.