PMID- 17547797
OWN - NLM
STAT- MEDLINE
DCOM- 20071129
LR  - 20140226
IS  - 0578-1426 (Print)
IS  - 0578-1426 (Linking)
VI  - 46
IP  - 3
DP  - 2007 Mar
TI  - [The reference values of glycemic parameters for continuous glucose monitoring 
      and its clinical application].
PG  - 189-92
AB  - OBJECTIVE: To establish reference values of glycemic parameters for continuous 
      glucose monitoring in Chinese. METHODS: Forty-eight individuals with normal 
      glucose regulation were observed with continuous glucose monitoring system (CGMS) 
      for 3 days. Indexes in CGMS were analyzed, including mean level of 24 h blood 
      glucose (BG) values (24 h MBG) and its standard deviation (SDBG), percentage of 
      time above 7.8 mmol/L or below 3.9 mmol/L, area under the curve (AUC) of BG above 
      5.6 mmol/L, the largest amplitude of glycemic excursions (LAGE), mean amplitude 
      of glycemic excursions (MAGE) and absolute means of daily differences (MODD). 
      RESULTS: (1) The upper limits of indexes for continuous glucose monitoring were 
      as follows: 6.5 mmol/L for 24 h MBG, 6.0 mmol/L, 6.3 mmol/L and 6.0 mmol/L for 
      mean BG levels 1 h before breakfast, lunch and dinner respectively, 7.0 mmol/L, 
      6.7 mmol/L and 7.0 mmol/L for mean BG levels 3 h after breakfast, lunch and 
      dinner respectively, 1.4 mmol/L for SDBG, 5.7 mmol/L for LAGE, 3.4 mmol/L for 
      MAGE and 1.4 mmol/L for MODD. The percentage of time over 7.8 mmol/L was less 
      than 9%, while the percentage of time below 3.9 mmol/L was less than 20%. The AUC 
      of BG above 5.6 mmol/L was less than 0.9 d x mmol x L(-1). There was no 
      statistical difference among sex subgroups (P > 0.05). (2) The correlations of 
      24h MBG with MAGE, MODD and SDBG were not significant (P > 0.05). MAGE was 
      positively correlated with SDBG (r = 0.93, P < 0.01). CONCLUSION: The reference 
      values of glycemic parameters for continuous glucose monitoring are initially 
      established and can be used as a temporary reference for clinical practice in 
      Chinese. The CGMS profile can reflect the overall BG control and the feature of 
      glycemic excursions in detail.
FAU - Zhou, Jian
AU  - Zhou J
AD  - Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Department of 
      Endocrinology and Metabolism, The Sixth People's Hospital, Affiliated to Jiaotong 
      University, Shanghai 200233, China.
FAU - Jia, Wei-ping
AU  - Jia WP
FAU - Yu, Ming
AU  - Yu M
FAU - Yu, Hao-yong
AU  - Yu HY
FAU - Bao, Yu-qian
AU  - Bao YQ
FAU - Ma, Xiao-jing
AU  - Ma XJ
FAU - Lu, Wei
AU  - Lu W
FAU - Hu, Cheng
AU  - Hu C
FAU - Xiang, Kun-san
AU  - Xiang KS
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhonghua Nei Ke Za Zhi
JT  - Zhonghua nei ke za zhi
JID - 16210490R
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Adult
MH  - Area Under Curve
MH  - Blood Glucose/*metabolism
MH  - China
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Monitoring, Physiologic/*standards
MH  - Reference Values
EDAT- 2007/06/06 09:00
MHDA- 2007/12/06 09:00
CRDT- 2007/06/06 09:00
PHST- 2007/06/06 09:00 [pubmed]
PHST- 2007/12/06 09:00 [medline]
PHST- 2007/06/06 09:00 [entrez]
PST - ppublish
SO  - Zhonghua Nei Ke Za Zhi. 2007 Mar;46(3):189-92.