PMID- 1755351
OWN - NLM
STAT- MEDLINE
DCOM- 19920128
LR  - 20131121
IS  - 0270-2304 (Print)
IS  - 0270-2304 (Linking)
VI  - 11
IP  - 3
DP  - 1991 Sep
TI  - Predicting the occurrence of antibiotic-induced candidal vaginitis (AICV).
PG  - 319-26
AB  - This paper reports the sensitivity, specificity, and predictive values of 
      symptoms in the diagnosis of antibiotic-induced candidal vaginitis (AICV) among 
      74 women recruited from three primary care practices. All subjects, who were 
      examined both pre- and post-antibiotic treatment for acute respiratory, urinary 
      tract, or skin infections, were initially free of vaginitis. Twenty-four subjects 
      developed candidal vaginitis (CV), indicated by vaginitis symptoms or signs and a 
      positive candidal culture or KOH preparation; there were no mixed infections. 
      Fifty women did not develop AICV and, of this group, four developed a nonyeast 
      vaginitis. Aggregate symptoms (pruritus and/or discharge) had 87.5% sensitivity, 
      95.8% specificity, and positive and negative predictive values of 91.3% and 
      93.9%, respectively. These values are much higher than those reported in studies 
      of CV that excluded women on antibiotics. We conclude that women who develop 
      vaginitis symptoms while on short courses of antibiotics may be treated as AICV 
      without confirmatory examination.
FAU - Bluestein, D
AU  - Bluestein D
AD  - Department of Family and Community Medicine, Eastern Virginia Medical School, 
      Norfolk 23501.
FAU - Rutledge, C
AU  - Rutledge C
FAU - Lumsden, L
AU  - Lumsden L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Fam Pract Res J
JT  - Family practice research journal
JID - 8208228
RN  - 0 (Anti-Bacterial Agents)
RN  - 63937KV33D (Erythromycin)
SB  - IM
MH  - Adult
MH  - Anti-Bacterial Agents/*adverse effects
MH  - Candidiasis, Vulvovaginal/*chemically induced
MH  - Erythromycin/pharmacology
MH  - Female
MH  - Humans
MH  - Incidence
MH  - Physical Examination
MH  - Vaginitis/*chemically induced
EDAT- 1991/09/01 00:00
MHDA- 1991/09/01 00:01
CRDT- 1991/09/01 00:00
PHST- 1991/09/01 00:00 [pubmed]
PHST- 1991/09/01 00:01 [medline]
PHST- 1991/09/01 00:00 [entrez]
PST - ppublish
SO  - Fam Pract Res J. 1991 Sep;11(3):319-26.