PMID- 1755379
OWN - NLM
STAT- MEDLINE
DCOM- 19920127
LR  - 20190622
IS  - 0065-2598 (Print)
IS  - 0065-2598 (Linking)
VI  - 305
DP  - 1991
TI  - Biological aspects of monocyte chemoattractant protein-1 (MCP-1).
PG  - 57-64
AB  - In this communication, we have asked if MCP-1 is the mediator of cellular 
      infiltration in DCH, outlining the criteria in Table 3. Preliminary data suggest 
      that PHA-stimulated lymphocytes secrete MCP-1, and that MCP-1 can be produced in 
      response to antigen stimulation. MCP-1 attracts monocytes and basophils, but not 
      neutrophils. The question of a lymphocyte response to MCP-1 requires further 
      study. We have emphasized that the discovery of leukocyte-specific NAP-1 and 
      MCP-1 should now be followed by exploration of conditions in which one agonist is 
      secreted without the other. This would be expected, for example, in DCH, which is 
      characterized by mononuclear leukocyte infiltration without neutrophils.
FAU - Leonard, E J
AU  - Leonard EJ
AD  - Immunopathology Section, National Cancer Institute, Frederick, Maryland.
FAU - Skeel, A
AU  - Skeel A
FAU - Yoshimura, T
AU  - Yoshimura T
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Adv Exp Med Biol
JT  - Advances in experimental medicine and biology
JID - 0121103
RN  - 0 (Chemokine CCL2)
RN  - 0 (Chemotactic Factors)
SB  - IM
MH  - Basophils/physiology
MH  - Chemokine CCL2
MH  - Chemotactic Factors/*immunology/metabolism/pharmacology
MH  - Humans
MH  - Hypersensitivity, Delayed/immunology
MH  - Immunity, Cellular
MH  - Lymphocytes/physiology
MH  - Monocytes/physiology
RF  - 15
EDAT- 1991/01/01 00:00
MHDA- 1991/01/01 00:01
CRDT- 1991/01/01 00:00
PHST- 1991/01/01 00:00 [pubmed]
PHST- 1991/01/01 00:01 [medline]
PHST- 1991/01/01 00:00 [entrez]
AID - 10.1007/978-1-4684-6009-4_7 [doi]
PST - ppublish
SO  - Adv Exp Med Biol. 1991;305:57-64. doi: 10.1007/978-1-4684-6009-4_7.