PMID- 17555971 OWN - NLM STAT- MEDLINE DCOM- 20071004 LR - 20101118 IS - 1010-7940 (Print) IS - 1010-7940 (Linking) VI - 32 IP - 2 DP - 2007 Aug TI - What to expect after tricuspid valve replacement? Long-term results. PG - 296-300 AB - OBJECTIVE: Current knowledge in long-term results of tricuspid valve replacement is limited. Present study reviews our experience from a consecutive series. METHODS: Forty-two patients (16 male, 26 female; mean age: 33+/-15) underwent tricuspid valve replacement between March 1987 and December 2004. The etiology was rheumatic in 64%, Ebstein's anomaly in 31%, and endocarditis in 5%. Nineteen patients were in New York Heart Association (NYHA) Class III functional capacity (45%), and 13 in class IV (31%). Twenty patients (48%) underwent isolated tricuspid valve replacement. The remaining underwent combined (mitral and/or aortic) valve replacements. Tricuspid replacement device was mechanical in 31% and bioimplant in 69%. RESULTS: Hospital mortality was 26%. Rheumatic etiology, reoperation and elevated pulmonary artery pressure were associated with higher early mortality. The patients with decreased functional capacity (NYHA Class III/IV), congestive symptoms and rheumatic origin were more prone to low cardiac output development. The Kaplan-Meier survivals were 37% at 10 years and 30% at 15 years. The 10-year event-free survival was 31%. Elevated pulmonary artery pressure and rheumatic etiology unfavorably affected the long-term results. The average functional capacity in survivors improved significantly after operation. CONCLUSIONS: Any tricuspid disease not amenable to repair thus necessitating replacement is an unfortunate situation since both the short and long-term results of valve replacement are suboptimal in regard to those of left-sided valve replacements, probably due to different structural and geometrical characteristics of right ventricle and the low-pressure venous system hemodynamics. Etiology, clinical presentation and pulmonary vascular hemodynamics are major determinants of the outcome. FAU - Iscan, Zafer H AU - Iscan ZH AD - Department of Cardiovascular Surgery, Yuksek Ihtisas Hospital of Turkey, Ankara, Turkey. FAU - Vural, Kerem M AU - Vural KM FAU - Bahar, Ilknur AU - Bahar I FAU - Mavioglu, Levent AU - Mavioglu L FAU - Saritas, Ahmet AU - Saritas A LA - eng PT - Journal Article DEP - 20070606 PL - Germany TA - Eur J Cardiothorac Surg JT - European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery JID - 8804069 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Bioprosthesis MH - Blood Pressure/physiology MH - Cardiac Output, Low/complications/physiopathology MH - Child MH - Ebstein Anomaly/complications/physiopathology MH - Female MH - Heart Failure/complications/physiopathology MH - Heart Valve Diseases/etiology/physiopathology/*surgery MH - Heart Valve Prosthesis Implantation/*methods/mortality MH - Humans MH - Kaplan-Meier Estimate MH - Male MH - Middle Aged MH - Postoperative Complications MH - Pulmonary Artery/physiopathology MH - Reoperation MH - Rheumatic Diseases/complications/physiopathology MH - Risk Factors MH - Time Factors MH - Treatment Outcome MH - Tricuspid Valve/*surgery EDAT- 2007/06/09 09:00 MHDA- 2007/10/05 09:00 CRDT- 2007/06/09 09:00 PHST- 2007/03/14 00:00 [received] PHST- 2007/04/13 00:00 [revised] PHST- 2007/05/07 00:00 [accepted] PHST- 2007/06/09 09:00 [pubmed] PHST- 2007/10/05 09:00 [medline] PHST- 2007/06/09 09:00 [entrez] AID - S1010-7940(07)00437-X [pii] AID - 10.1016/j.ejcts.2007.05.003 [doi] PST - ppublish SO - Eur J Cardiothorac Surg. 2007 Aug;32(2):296-300. doi: 10.1016/j.ejcts.2007.05.003. Epub 2007 Jun 6.