PMID- 17564346 OWN - NLM STAT- MEDLINE DCOM- 20070731 LR - 20070613 IS - 1660-9379 (Print) IS - 1660-9379 (Linking) VI - 3 IP - 110 DP - 2007 May 9 TI - [Myasthenia gravis: treatments and remissions]. PG - 1185-6, 1188-90 AB - Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction, due to the binding of autoantibodies to the nicotinic acetylcholine receptor (AChR), or more rarely to a muscle specific kinase (MuSK). It affects most of the time young women and old patients, with a tendency toward increasing incidence and prevalence. Clinical presentation, with fluctuating weakness of ocular, facial and bulbar muscles has a wide range of severity. Evolution is characterized by remissions and exacerbations. The goal of treatment is a complete remission, which implies a sustained collaboration between the general practitioner and the specialized centre and the use of symptomatic treatment (anticholinesterasic) in association with immunomodulators/suppressors (prednisone and azathioprine); although other treatments are available. FAU - Dunand, Murielle AU - Dunand M AD - Unite nerf-muscle, Service de neurologie, CHUV, 1011 Lausanne. murielle.dunand@chuv.ch FAU - Lalive, Patrice H AU - Lalive PH FAU - Vokatch, Natalia AU - Vokatch N FAU - Kuntzer, Thierry AU - Kuntzer T LA - fre PT - English Abstract PT - Journal Article PT - Review TT - Myasthenie grave, traitements et remissions. PL - Switzerland TA - Rev Med Suisse JT - Revue medicale suisse JID - 101219148 SB - IM MH - Humans MH - Myasthenia Gravis/*diagnosis/*drug therapy MH - Remission Induction RF - 16 EDAT- 2007/06/15 09:00 MHDA- 2007/08/01 09:00 CRDT- 2007/06/15 09:00 PHST- 2007/06/15 09:00 [pubmed] PHST- 2007/08/01 09:00 [medline] PHST- 2007/06/15 09:00 [entrez] PST - ppublish SO - Rev Med Suisse. 2007 May 9;3(110):1185-6, 1188-90.