PMID- 17565312
OWN - NLM
STAT- MEDLINE
DCOM- 20070731
LR  - 20070613
IS  - 0041-1337 (Print)
IS  - 0041-1337 (Linking)
VI  - 83
IP  - 11
DP  - 2007 Jun 15
TI  - Balancing organ quality, HLA-matching, and waiting times: impact of a pediatric 
      priority allocation policy for deceased donor kidneys in Quebec.
PG  - 1411-5
AB  - Deceased donor kidney allocation policy must balance the desire for high-quality 
      organs, good human leukocyte antigen (HLA) matching, and minimal waiting times. 
      We describe a 10-fold reduction in waiting times and an improvement in 
      nonimmunologic indices of organ quality for child recipients after a change in 
      organ allocation policy in Quebec, Canada. The new policy gives first priority to 
      children (<18 yr) irrespective of HLA matching or waiting time. HLA matching 
      after the policy change was predictably much worse. This study highlights the 
      trade-offs that must be considered both in setting allocation policy and in 
      decisions for individual recipients. We also consider potential unintended 
      negative effects of such a policy change.
FAU - Crafter, Samuel R
AU  - Crafter SR
AD  - Department of Pediatrics, Division of Nephrology (E-222), Montreal Children's 
      Hospital, McGill University School of Medicine, Montreal, Canada.
FAU - Bell, Lorraine
AU  - Bell L
FAU - Foster, Bethany J
AU  - Foster BJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Transplantation
JT  - Transplantation
JID - 0132144
SB  - IM
MH  - Adolescent
MH  - Cadaver
MH  - Child
MH  - Child, Preschool
MH  - *Health Care Rationing
MH  - *Health Policy
MH  - *Histocompatibility Testing
MH  - Humans
MH  - Infant
MH  - Kidney/*physiopathology
MH  - Quebec
MH  - Time Factors
MH  - *Tissue and Organ Procurement
MH  - *Waiting Lists
EDAT- 2007/06/15 09:00
MHDA- 2007/08/01 09:00
CRDT- 2007/06/15 09:00
PHST- 2007/06/15 09:00 [pubmed]
PHST- 2007/08/01 09:00 [medline]
PHST- 2007/06/15 09:00 [entrez]
AID - 00007890-200706150-00001 [pii]
AID - 10.1097/01.tp.0000266580.19614.f7 [doi]
PST - ppublish
SO  - Transplantation. 2007 Jun 15;83(11):1411-5. doi: 
      10.1097/01.tp.0000266580.19614.f7.