PMID- 1756762 OWN - NLM STAT- MEDLINE DCOM- 19920206 LR - 20180214 IS - 0014-3022 (Print) IS - 0014-3022 (Linking) VI - 31 IP - 6 DP - 1991 TI - Genetic aspects of nonconvulsive status epilepticus. PG - 384-7 AB - We studied the occurrence of seizure disorders within the immediate family in 3 groups of probands: (1) 64 epileptic children with nonconvulsive status epilepticus (NCSE); (2) 454 epileptic children who have had no episodes of NCSE; (3) 306 healthy children, matched for age and sex. Recurrence of seizures among relatives of epileptic probands without NCSE was significantly higher than among the general population, both in generalized and partial epilepsies. We also observed an increased incidence of convulsions among the relatives of probands with NCSE and the general population; no differences were noted between epileptic children with or without NCSE. These data support the hypothesis that genetic factors play an important role in the etiology of seizure disorders in children with NCSE. FAU - Brinciotti, M AU - Brinciotti M AD - Istituto di Neuropsichiatria Infantile, Universita La Sapienza, Roma, Italia. FAU - Mazzei, C AU - Mazzei C FAU - Galletti, F AU - Galletti F FAU - Matricardi, M AU - Matricardi M LA - eng PT - Journal Article PL - Switzerland TA - Eur Neurol JT - European neurology JID - 0150760 SB - IM MH - Adolescent MH - Brain Damage, Chronic/diagnosis/genetics MH - Child MH - Child, Preschool MH - Electroencephalography MH - Epilepsies, Partial/diagnosis/*genetics MH - Epilepsy, Generalized/diagnosis/*genetics MH - Female MH - Humans MH - Infant MH - Male MH - Neurologic Examination MH - Status Epilepticus/diagnosis/*genetics EDAT- 1991/01/01 00:00 MHDA- 1991/01/01 00:01 CRDT- 1991/01/01 00:00 PHST- 1991/01/01 00:00 [pubmed] PHST- 1991/01/01 00:01 [medline] PHST- 1991/01/01 00:00 [entrez] AID - 10.1159/000116699 [doi] PST - ppublish SO - Eur Neurol. 1991;31(6):384-7. doi: 10.1159/000116699.