PMID- 17568129
OWN - NLM
STAT- MEDLINE
DCOM- 20070712
LR  - 20070614
IS  - 1064-3745 (Print)
IS  - 1064-3745 (Linking)
VI  - 366
DP  - 2007
TI  - Developing computational resources in cardiac gene expression.
PG  - 253-63
AB  - The development of biotechnology and the completion of the Human Genome Project 
      have led to the rapid emergence of enormous amounts of genomic information. 
      Computational resources are needed to enable researchers and clinicians to obtain 
      quick, up-to-date information in targeted areas. The creation of this type of 
      subject-specific knowledge base requires expertise in diverse fields. This 
      chapter is meant to provide a detailed overview and blueprint for how to 
      construct a cardiac-specific knowledge base like the Human Cardiac Gene 
      Expression Knowledge Base (CaGE) (1). We have provided an overview of some of the 
      ways to capture, organize, and store the necessary data using Perl scripts. Each 
      group or individual interested in developing a cardiac or gene expression 
      knowledge base will have unique needs. We hope that this information will serve 
      as a guide for the development of new computational tools.
FAU - Bober, Michael B
AU  - Bober MB
AD  - Division of Medical Genetics, A.I. DuPont Hospital for Children, Wilmington, DE, 
      USA.
FAU - Winslow, Raimond
AU  - Winslow R
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Methods Mol Biol
JT  - Methods in molecular biology (Clifton, N.J.)
JID - 9214969
SB  - IM
MH  - Animals
MH  - Computational Biology/*methods
MH  - Databases, Factual
MH  - Gene Expression/*physiology
MH  - Humans
MH  - Myocardium/*metabolism
EDAT- 2007/06/15 09:00
MHDA- 2007/07/13 09:00
CRDT- 2007/06/15 09:00
PHST- 2007/06/15 09:00 [pubmed]
PHST- 2007/07/13 09:00 [medline]
PHST- 2007/06/15 09:00 [entrez]
AID - 1-59745-030-8:253 [pii]
AID - 10.1007/978-1-59745-030-0_14 [doi]
PST - ppublish
SO  - Methods Mol Biol. 2007;366:253-63. doi: 10.1007/978-1-59745-030-0_14.