PMID- 17569582
OWN - NLM
STAT- MEDLINE
DCOM- 20080204
LR  - 20071015
IS  - 1389-9457 (Print)
IS  - 1389-9457 (Linking)
VI  - 8
IP  - 7-8
DP  - 2007 Nov
TI  - REM behavior disorder (RBD) can be one of the first symptoms of childhood 
      narcolepsy.
PG  - 784-6
AB  - More than one in three adult patients suffering from narcolepsy-cataplexy 
      experience rapid eye movement (REM) behavior disorder (RBD), while RBD in 
      childhood is extremely rare. We present the cases of two girls (aged 9 and 7 
      years old) with narcolepsy-cataplexy, in whom RBD was one of the first symptoms 
      of the disease. The coincidence of RBD was seen by nocturnal 
      video-polysomnography (v-PSG), and narcolepsy was diagnosed from short sleep 
      latency and multiple sleep onset REMs (SOREMs) during a multiple sleep latency 
      test (MSLT). Both girls were human leukocyte antigen (HLA)-DQB1 *0602 positive, 
      and their cerebrospinal fluid (CSF) hypocretin level (Hcrt-1) was extremely low.
FAU - Nevsimalova, Sona
AU  - Nevsimalova S
AD  - Department of Neurology, 1st Medical Faculty, Charles University, Prague, Czech 
      Republic. snevsi@lfl1.cuni.cz
FAU - Prihodova, Iva
AU  - Prihodova I
FAU - Kemlink, David
AU  - Kemlink D
FAU - Lin, Ling
AU  - Lin L
FAU - Mignot, Emmanuel
AU  - Mignot E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20070613
PL  - Netherlands
TA  - Sleep Med
JT  - Sleep medicine
JID - 100898759
SB  - IM
MH  - Child
MH  - Female
MH  - Humans
MH  - Narcolepsy/complications/*diagnosis
MH  - Polysomnography
MH  - REM Sleep Behavior Disorder/complications/*diagnosis
MH  - Severity of Illness Index
MH  - Sleep, REM/physiology
EDAT- 2007/06/16 09:00
MHDA- 2008/02/05 09:00
CRDT- 2007/06/16 09:00
PHST- 2006/10/09 00:00 [received]
PHST- 2006/11/21 00:00 [revised]
PHST- 2006/11/26 00:00 [accepted]
PHST- 2007/06/16 09:00 [pubmed]
PHST- 2008/02/05 09:00 [medline]
PHST- 2007/06/16 09:00 [entrez]
AID - S1389-9457(06)00713-1 [pii]
AID - 10.1016/j.sleep.2006.11.018 [doi]
PST - ppublish
SO  - Sleep Med. 2007 Nov;8(7-8):784-6. doi: 10.1016/j.sleep.2006.11.018. Epub 2007 Jun 
      13.