PMID- 17574864
OWN - NLM
STAT- MEDLINE
DCOM- 20071127
LR  - 20181201
IS  - 1047-2797 (Print)
IS  - 1047-2797 (Linking)
VI  - 17
IP  - 9
DP  - 2007 Sep
TI  - Concurrent vaccinations and U.S. military hospitalizations.
PG  - 697-703
AB  - PURPOSE: To investigate whether concurrent vaccinations (> or =2 vaccinations on 
      consecutive days) are associated with hospitalization risk among U.S. military 
      personnel. METHODS: We analyzed Defense Medical Surveillance System data from 
      January 1998 through December 2003 for 117,876 active component U.S. military 
      personnel. We performed a time-to-event analysis of a historical cohort using a 
      Cox proportional hazards model comparing hospitalizations during a 120-day 
      postvaccination exposure interval to hospitalizations within a 120-day 
      pre-exposure interval. We excluded personnel who were deployed during these 
      intervals and those having hospitalizations 60 days prior to the concurrent 
      vaccination exposure. Hazards ratios (HRs) with 95% confidence intervals were 
      calculated, adjusting for demographic, occupational, health, and calendar 
      variables. RESULTS: We analyzed 19,743 persons having concurrent vaccinations. 
      Receiving two or more vaccinations concurrently was not statistically associated 
      with the adjusted risk of hospitalization (HR = 0.90 [0.75, 1.09]). Furthermore, 
      no statistically significant associations were detected for 3 concurrent 
      vaccinations (HR = 0.86 [0.58, 1.28]), 4 concurrent vaccinations (HR = 1.08, 
      [0.66, 1.74]), or five or more concurrent vaccinations (HR = 0.86 [0.49, 1.51]). 
      CONCLUSIONS: No evidence was found that the concurrent receipt of multiple 
      vaccinations is related to hospitalization risk among this sample of U.S. 
      military personnel.
FAU - Payne, Daniel C
AU  - Payne DC
AD  - Bacterial Vaccine-Preventable Disease Branch, Epidemiology and Surveillance 
      Division, National Immunization Program, Centers for Disease Control and 
      Prevention, Atlanta, GA 30333, USA. dvp6@cdc.gov
FAU - Aranas, Aaron
AU  - Aranas A
FAU - McNeil, Michael M
AU  - McNeil MM
FAU - Duderstadt, Susan
AU  - Duderstadt S
FAU - Rose, Charles E Jr
AU  - Rose CE Jr
LA  - eng
PT  - Journal Article
DEP - 20070615
PL  - United States
TA  - Ann Epidemiol
JT  - Annals of epidemiology
JID - 9100013
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Confidence Intervals
MH  - Female
MH  - *Hospitalization
MH  - Humans
MH  - Immunization/*statistics & numerical data
MH  - Male
MH  - Middle Aged
MH  - *Military Personnel
MH  - Proportional Hazards Models
MH  - United States
EDAT- 2007/06/19 09:00
MHDA- 2007/12/06 09:00
CRDT- 2007/06/19 09:00
PHST- 2006/09/18 00:00 [received]
PHST- 2007/03/09 00:00 [revised]
PHST- 2007/03/29 00:00 [accepted]
PHST- 2007/06/19 09:00 [pubmed]
PHST- 2007/12/06 09:00 [medline]
PHST- 2007/06/19 09:00 [entrez]
AID - S1047-2797(07)00152-4 [pii]
AID - 10.1016/j.annepidem.2007.03.018 [doi]
PST - ppublish
SO  - Ann Epidemiol. 2007 Sep;17(9):697-703. doi: 10.1016/j.annepidem.2007.03.018. Epub 
      2007 Jun 15.